A therapeutic strategy that targets multiple proinflammatory factors in inflammatory bowel
disease (IBD) with minimal systemic side effects would be attractive. Here, we develop a …

Benefiting from the evolution of nanotechnology, the combination therapy by gene
interference and reactive oxygen species (ROS) scavenging are expected, which holds …

Severe sepsis represents a common, expensive, and deadly health care issue with limited
therapeutic options. Gaining insights into the inflammatory dysregulation that causes sepsis …

Inflammatory bowel disease (IBD) is a chronic, idiopathic inflammatory set of conditions that
can affect the entire gastrointestinal (GI) tract and is associated with an increased risk of …

As a group of chronic and idiopathic gastrointestinal (GI) disorders, inflammatory bowel
disease (IBD) is characterized by recurrent intestinal mucosal inflammation. Oral …

Inflammatory bowel disease (IBD) is an incurable disease of the gastrointestinal tract with a
lack of effective therapeutic strategies. The proinflammatory microenvironment plays a …

Oxidative stress, resulting from excessive generation of reactive oxygen species (ROS),
plays a pivotal role in the initiation and progression of inflammatory bowel disease (IBD). To …

Inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis
(UC), is characterized by chronic relapsing inflammation of the gastrointestinal tract. Delivery …

Combination therapy is an emerging strategy that is under intensive preclinical investigation
for the treatment of various diseases. CD98 is highly overexpressed on the surfaces of …

Developing oral nanomedicines that suppress intestinal inflammation while modulating gut
microbiota and brain interactions is essential for effectively treating inflammatory bowel …