Background Variation in the course of major depressive disorder (MDD) is not strongly
predicted by existing subtype distinctions. A new subtyping approach is considered here …

Background. Although variation in the long-term course of major depressive disorder (MDD)
is not strongly predicted by existing symptom subtype distinctions, recent research suggests …

Background According to current classification systems, patients with major depressive
disorder (MDD) may have very different combinations of symptoms. This symptomatic …

Objective: The heterogeneity of depression in the current classification system remains a
point of discussion in the psychiatric field, despite previous efforts to subclassify depressive …

Background In recent years, researchers have used various techniques to elucidate the
heterogeneity in depressive symptoms. This study seeks to resolve the extent to which …

Background Two-thirds of major depressive disorder (MDD) patients initially present with
somatic symptoms, yet no study has used approaches based on somatic symptoms to …

BACKGROUND: Continued research efforts aim to elucidate the heterogeneity in
depression. The identification of meaningful and valid subtypes has implications for …

Heterogeneity of major depressive disorder (MDD) illness course complicates clinical
decision-making. Although efforts to use symptom profiles or biomarkers to develop clinically …

Background The course-heterogeneity of Major Depressive Disorder (MDD) hampers
development of better prognostic models. Although latent class growth analyses (LCGA) …

BACKGROUND: Increasing dissatisfaction with the non-specificity of major depression has
led many to propose more specific depressive subtyping models. The present meta-review …