[HTML][HTML] Ionotropic gelation and chemical crosslinking as methods for fabrication of modified-release gellan gum-based drug delivery systems

P Gadziński, A Froelich, B Jadach, M Wojtyłko… - Pharmaceutics, 2023 - mdpi.com
Hydrogels have a tridimensional structure. They have the ability to absorb a significant
amount of water or other natural or simulated fluids that cause their swelling albeit without …

Preparation and characterization of novel gellan gum hydrogels suitable for modified drug release

P Matricardi, C Cencetti, R Ria, F Alhaique, T Coviello - Molecules, 2009 - mdpi.com
Innovative hydrogels obtained by physical and chemical crosslinking of deacylated Gellan
gum have been characterized in terms of water uptake, rheological properties and …

Fabrication methods and form factors of gellan gum-based materials for drug delivery and anti-cancer applications

C Villarreal-Otalvaro, JM Coburn - ACS Biomaterials Science & …, 2021 - ACS Publications
Despite the success of cancer therapeutics, off target cell toxicity prevails as one of the main
challenges of cancer treatment. Exploration of drug delivery methods is a growing field of …

Gum-based hydrogels in drug delivery

AK Nayak, MS Hasnain, K Pal, I Banerjee… - Biopolymer-based …, 2020 - Elsevier
Hydrogels are three-dimensional cross-linked networks generally composed of hydrophilic
polymers having the capability to hold high volume of aqueous fluids devoid of altering the …

Gellan gum in drug delivery applications

M Milivojevic, I Pajic-Lijakovic, B Bugarski… - … polysaccharides in drug …, 2019 - Elsevier
The different techniques that enable drug delivery in the desired manner are constantly
investigated and developed to enhance patient compliance and drug efficiency and to …

Modified gellan gum hydrogels for tissue engineering applications

CJ Ferris, KJ Gilmore, GG Wallace - Soft Matter, 2013 - pubs.rsc.org
Gellan gum is an anionic linear polysaccharide well known for its use as a multi-functional
gelling, stabilising and suspending agent in a variety of foods and personal care products. In …

Injectable and photocross-linkable gels based on gellan gum methacrylate: A new tool for biomedical application

S Pacelli, P Paolicelli, I Dreesen, S Kobayashi… - International journal of …, 2015 - Elsevier
In this work, a natural polysaccharide gellan gum (GG) has been modified with methacrylic
groups (GG-MA) and combined with polyethylene glycol dimethacrylate (PEG-DMA) in order …

Hydrogels based on gellan gum in cell delivery and drug delivery

M Das, TK Giri - Journal of Drug Delivery Science and Technology, 2020 - Elsevier
Gellan gum is a green biopolymer widely used in pharmaceuticals, cosmetics and food
industries as suspending, stabilizing, and thickening agent. It is able to form hydrogels with …

Gellan gum-based delivery systems of therapeutic agents and cells

FS Palumbo, S Federico, G Pitarresi, C Fiorica… - Carbohydrate …, 2020 - Elsevier
The purpose of this review is to make a summary of high quality research trends using
gellan gum (GG) as a polymeric constituent for the design of innovative drug delivery …

Swelling of high acyl gellan gum hydrogel: Characterization of network strengthening and slower release

KM Kanyuck, TB Mills, IT Norton… - Carbohydrate Polymers, 2021 - Elsevier
This study examined the mechanism of swelling for high acyl (HA) gellan gum and the
impacts on the hydrogel mechanical properties and the release of a model drug (glucose) …