Cellular and molecular mechanisms involved in the neurotoxicity of opioid and psychostimulant drugs

T Cunha-Oliveira, AC Rego, CR Oliveira - Brain research reviews, 2008 - Elsevier
Substance abuse and addiction are the most costly of all the neuropsychiatric disorders. In
the last decades, much progress has been achieved in understanding the effects of the …

Neurotoxicity of substituted amphetamines: molecular and cellular mechanisms

JL Cadet, IN Krasnova, S Jayanthi, J Lyles - Neurotoxicity research, 2007 - Springer
The amphetamines, including amphetamine (AMPH), methamphetamine (METH) and 3, 4-
methylenedioxymethamphetamine (MDMA), are among abused drugs in the US and …

Molecular bases of methamphetamine-induced neurodegeneration

JL Cadet, IN Krasnova - International review of neurobiology, 2009 - Elsevier
Methamphetamine (METH) is a highly addictive psychostimulant drug, whose abuse has
reached epidemic proportions worldwide. The addiction to METH is a major public concern …

Dopamine-induced behavioral changes and oxidative stress in methamphetamine-induced neurotoxicity

T Kita, I Miyazaki, M Asanuma, M Takeshima… - International review of …, 2009 - Elsevier
High-dose administration of amphetamine-like compounds is associated with acute
behavioral toxicity (including stereotypic and self-injurious behavior and schizophrenic-like …

Psychostimulants and brain dysfunction: a review of the relevant neurotoxic effects

J Gonçalves, S Baptista, AP Silva - Neuropharmacology, 2014 - Elsevier
Psychostimulants abuse is a major public concern because is associated with serious health
complications, including devastating consequences on the central nervous system (CNS) …

Amphetamine-related drugs neurotoxicity in humans and in experimental animals: Main mechanisms

R Moratalla, A Khairnar, N Simola, N Granado… - Progress in …, 2017 - Elsevier
Amphetamine-related drugs, such as 3, 4-methylenedioxymethamphetamine (MDMA) and
methamphetamine (METH), are popular recreational psychostimulants. Several preclinical …

Molecular neurobiology of drug addiction

EJ Nestler - Neuropsychopharmacology, 1994 - nature.com
The purpose of this review is to illustrate the ways in which molecular neurobiological
investigations will contribute to an improved understanding of drug addiction and, ultimately …

[图书][B] Drugs, addiction, and the brain

GF Koob, MA Arends, M Le Moal - 2014 - books.google.com
Drugs, Addiction, and the Brain explores the molecular, cellular, and neurocircuitry systems
in the brain that are responsible for drug addiction. Common neurobiological elements are …

Addiction and the brain: the role of neurotransmitters in the cause and treatment of drug dependence

DM Tomkins, EM Sellers - Cmaj, 2001 - Can Med Assoc
RECENT SCIENTIFIC ADVANCES HAVE LED to a greater understanding of the
neurobiological processes that underlie drug abuse and addiction. These suggest that …

[HTML][HTML] Neurobiology of opioid dependence in creating addiction vulnerability

CJ Evans, CM Cahill - F1000Research, 2016 - ncbi.nlm.nih.gov
Opioid drugs are potent modulators of many physiological and psychological processes.
When given acutely, they can elicit the signature responses of euphoria and analgesia that …