Carbamazepine facilitated horizontal transfer of antibiotic resistance genes by enhancing microbial communication and aggregation

Y Xiang, M Jia, R Xu, J Xu, L He, H Peng, W Sun… - Bioresource …, 2024 - Elsevier
Antimicrobial resistance is a global health security issue of widespread concern. Recent
studies have unveiled the potential contribution of non-antibiotics to the emergence of …

Combined exposure to non-antibiotic pharmaceutics and antibiotics in the gut synergistically promote the development of multi-drug-resistance in Escherichia coli

D Shi, H Hao, Z Wei, D Yang, J Yin, H Li, Z Chen… - Gut …, 2022 - Taylor & Francis
The gut microbiota represents an important reservoir of antibiotic-resistant bacteria (ARB),
which poses a significant threat to public health. However, little is known about the …

Dissemination of antibiotic resistance under antibiotics pressure during anaerobic co-digestion of food waste and sludge: Insights of driving factors, genetic expression …

P Wang, D Wu, Y Su, X Li, B Xie - Bioresource Technology, 2022 - Elsevier
This study revealed the effects and regulation mechanisms on antibiotic resistance genes
(ARGs) dissemination during anaerobic co-digestion (AcoD) of food waste and sludge under …

Deciphering the transfers of antibiotic resistance genes under antibiotic exposure conditions: driven by functional modules and bacterial community

Q Zhao, W Guo, H Luo, C Xing, H Wang, B Liu, Q Si… - Water Research, 2021 - Elsevier
Antibiotics can exert selective pressures on sludge as well as affect the emergence and
spread of antibiotic resistance genes (ARGs). However, the underlying mechanisms of …

Antiepileptic drug carbamazepine promotes horizontal transfer of plasmid-borne multi-antibiotic resistance genes within and across bacterial genera

Y Wang, J Lu, L Mao, J Li, Z Yuan, PL Bond… - The ISME …, 2019 - academic.oup.com
Antibiotic resistance is a severe global threat for public health, causing around 700,000
deaths per year. Horizontal gene transfer (HGT) is one of the most significant pathways to …

Disinfectant polyhexamethylene guanidine triggered simultaneous efflux pump antibiotic-and metal-resistance genes propagation during sludge anaerobic digestion

F Wang, W Huang, M Zhang, Q Zhang, Y Luo… - Environmental …, 2024 - Elsevier
The environmental transmission of antibiotic resistance genes (ARGs) and metal resistance
genes (MRGs) exerted devastating threats to global public health, and their interactions with …

Antidepressants promote the spread of extracellular antibiotic resistance genes via transformation

J Lu, P Ding, Y Wang, J Guo - ISME communications, 2022 - academic.oup.com
The development of antibiotic resistance as an unavoidable consequence of the application
of antimicrobials is a significant concern for human health. Antidepressants are being …

Exposure to benzalkonium chloride disinfectants promotes antibiotic resistance in sewage sludge microbiomes

K Yang, ML Chen, D Zhu - Science of The Total Environment, 2023 - Elsevier
Disinfectants are routinely used in human environments to control and prevent the
transmission of microbial disease, and this is particularly true during the current COVID-19 …

Non-antibiotic pharmaceuticals enhance the transmission of exogenous antibiotic resistance genes through bacterial transformation

Y Wang, J Lu, J Engelstädter, S Zhang, P Ding… - The ISME …, 2020 - academic.oup.com
Antibiotic resistance is a serious global threat for public health. Considering the high
abundance of cell-free DNA encoding antibiotic resistance genes (ARGs) in both clinical …

Artificial sweetener enhances the spread of antibiotic resistance genes during anaerobic digestion

G Yang, JM Cao, HL Cui, XM Zhan… - … Science & Technology, 2023 - ACS Publications
Artificial sweeteners have been frequently detected in the feedstocks of anaerobic digestion.
As these sweeteners can lead to the shift of anaerobic microbiota in the gut similar to that …