[HTML][HTML] REBUS and the anarchic brain: toward a unified model of the brain action of psychedelics

RL Carhart-Harris, KJ Friston - Pharmacological reviews, 2019 - ASPET
This paper formulates the action of psychedelics by integrating the free-energy principle and
entropic brain hypothesis. We call this formulation relaxed beliefs under psychedelics …

Unifying theories of psychedelic drug effects

LR Swanson - Frontiers in pharmacology, 2018 - frontiersin.org
How do psychedelic drugs produce their characteristic range of acute effects in perception,
emotion, cognition, and sense of self? How do these effects relate to the clinical efficacy of …

[HTML][HTML] The mechanistic divide in psychedelic neuroscience: An unbridgeable gap?

BR Barksdale, MK Doss, GA Fonzo, CB Nemeroff - Neurotherapeutics, 2024 - Elsevier
In recent years, psychedelics have generated considerable excitement and interest as
potential novel therapeutics for an array of conditions, with the most advanced evidence …

A complex systems perspective on psychedelic brain action

M Girn, FE Rosas, RE Daws, CL Gallen… - Trends in Cognitive …, 2023 - cell.com
Recent findings suggesting the potential transdiagnostic efficacy of psychedelic-assisted
therapy have fostered the need to deepen our understanding of psychedelic brain action …

[HTML][HTML] Pharmacological, neural, and psychological mechanisms underlying psychedelics: A critical review

M van Elk, DB Yaden - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
This paper provides a critical review of several possible mechanisms at different levels of
analysis underlying the effects and therapeutic potential of psychedelics. At the (1) …

Psychedelics and the essential importance of context

RL Carhart-Harris, L Roseman… - Journal of …, 2018 - journals.sagepub.com
Psychedelic drugs are making waves as modern trials support their therapeutic potential
and various media continue to pique public interest. In this opinion piece, we draw attention …

How do psychedelics work?

RL Carhart-Harris - Current opinion in psychiatry, 2019 - journals.lww.com
It is proposed that psychedelics initiate a cascade of neurobiological changes that manifest
at multiple scales and ultimately culminate in the relaxation of high-level beliefs. The …

[HTML][HTML] More than meets the eye: The role of sensory dimensions in psychedelic brain dynamics, experience, and therapeutics

M Aqil, L Roseman - Neuropharmacology, 2023 - Elsevier
Psychedelics are undergoing a major resurgence of scientific and clinical interest. While
multiple theories and frameworks have been proposed, there is yet no universal agreement …

Psychedelics and consciousness: Distinctions, demarcations, and opportunities

DB Yaden, MW Johnson, RR Griffiths… - International Journal …, 2021 - academic.oup.com
Psychedelic substances produce unusual and compelling changes in conscious experience
that have prompted some to propose that psychedelics may provide unique insights …

The challenges ahead for psychedelic 'medicine'

S Muthukumaraswamy, A Forsyth… - Australian & New …, 2022 - journals.sagepub.com
With the extensive public, commercial and scientific interest from what has been widely
termed the psychedelic renaissance, it is important that the scientific practices and results …