The global regulator Crc modulates metabolism, susceptibility to antibiotics and virulence in Pseudomonas aeruginosa
The capacity of a bacterial pathogen to produce a disease in a treated host depends on the
former's virulence and resistance to antibiotics. Several scattered pieces of evidence …
former's virulence and resistance to antibiotics. Several scattered pieces of evidence …
Carbon catabolite repression in Pseudomonas: optimizing metabolic versatility and interactions with the environment
F Rojo - FEMS microbiology reviews, 2010 - academic.oup.com
Metabolically versatile free-living bacteria have global regulation systems that allow cells to
selectively assimilate a preferred compound among a mixture of several potential carbon …
selectively assimilate a preferred compound among a mixture of several potential carbon …
[HTML][HTML] Virulence and Metabolism Crosstalk: Impaired Activity of the Type Three Secretion System (T3SS) in a Pseudomonas aeruginosa Crc-Defective Mutant
T Gil-Gil, T Cuesta, S Hernando-Amado… - International Journal of …, 2023 - mdpi.com
Pseudomonas aeruginosa is a ubiquitous nosocomial opportunistic pathogen that harbors
many virulence determinants. Part of P. aeruginosa success colonizing a variety of habitats …
many virulence determinants. Part of P. aeruginosa success colonizing a variety of habitats …
Metabolic regulation of antibiotic resistance
JL Martínez, F Rojo - FEMS microbiology reviews, 2011 - academic.oup.com
It is generally assumed that antibiotics and resistance determinants are the task forces of a
biological warfare in which each resistance determinant counteracts the activity of a specific …
biological warfare in which each resistance determinant counteracts the activity of a specific …
The Global Carbon Metabolism Regulator Crc Is a Component of a Signal Transduction Pathway Required for Biofilm Development by Pseudomonas aeruginosa
GA O'Toole, KA Gibbs, PW Hager… - Journal of …, 2000 - Am Soc Microbiol
The transition from a planktonic (free-swimming) existence to growth attached to a surface in
a biofilm occurs in response to environmental factors, including the availability of nutrients …
a biofilm occurs in response to environmental factors, including the availability of nutrients …
[HTML][HTML] Novel Targets of the CbrAB/Crc Carbon Catabolite Control System Revealed by Transcript Abundance in Pseudomonas aeruginosa
The opportunistic human pathogen Pseudomonas aeruginosa is able to utilize a wide range
of carbon and nitrogen compounds, allowing it to grow in vastly different environments. The …
of carbon and nitrogen compounds, allowing it to grow in vastly different environments. The …
The catabolite repression control protein Crc plays a role in the development of antimicrobial-tolerant subpopulations in Pseudomonas aeruginosa biofilms
L Zhang, WC Chiang, Q Gao, M Givskov… - …, 2012 - microbiologyresearch.org
Bacteria form complex surface-attached biofilm communities in nature. Biofilm cells
differentiate into subpopulations which display tolerance towards antimicrobial agents …
differentiate into subpopulations which display tolerance towards antimicrobial agents …
The Pseudomonas aeruginosa CreBC two-component system plays a major role in the response to β-lactams, fitness, biofilm growth, and global regulation
Pseudomonas aeruginosa is a ubiquitous versatile environmental microorganism with a
remarkable ability to grow under diverse environmental conditions. Moreover, P. aeruginosa …
remarkable ability to grow under diverse environmental conditions. Moreover, P. aeruginosa …
[HTML][HTML] The Transcriptional Regulator CzcR Modulates Antibiotic Resistance and Quorum Sensing in Pseudomonas aeruginosa
G Dieppois, V Ducret, O Caille, K Perron - PloS one, 2012 - journals.plos.org
The opportunistic pathogen Pseudomonas aeruginosa responds to zinc, cadmium and
cobalt by way of the CzcRS two-component system. In presence of these metals the …
cobalt by way of the CzcRS two-component system. In presence of these metals the …
Levels and Activity of the Pseudomonas putida Global Regulatory Protein Crc Vary According to Growth Conditions
The global regulatory protein Crc is involved in the repression of several catabolic pathways
for sugars, hydrocarbons, and nitrogenated and aromatic compounds in Pseudomonas …
for sugars, hydrocarbons, and nitrogenated and aromatic compounds in Pseudomonas …