Transcription factors of the SOX family were first discovered in mammals in 1990. The sex-
determining region Y box 9 belongs to the SOX transcription factor family. It plays an …

Sex-determining region Y-related high-mobility-group box transcription factor 11 (SOX11) is
an essential member of the SOX transcription factors and has been highlighted as an …

Ovarian cancer is one of the most common cancers which cause female mortality. The
knowledge of ovarian cancer initiation and progression is critical to develop new therapeutic …

Endometrial carcinoma (EC) remains one of the most prevalent forms of cancer to impact the
female reproductive system, yet the mechanisms governing its development and …

SOX2 is a gene that encodes for a transcription factor belonging to the SOX gene family and
contains a high-mobility group (HMG) domain, which permits highly specific DNA binding …

SOX9 [sex-determining region Y (SRY)-box 9 protein], a high mobility group box
transcription factor, plays critical roles during embryogenesis and its activity is required for …

Background Y-box member SOX9 determines sex. This family's eight subgroups (A–H) have
one to three members each. Sox gene transcription factors are critical for development and …

The distinction of ovarian Sertoli cell tumor from other tumors in the histological differential
diagnosis, particularly endometrioid carcinoma and carcinoid tumor, may be difficult. Many …

SOX7 belongs to the SOX (SRY-related HMG-box) family of transcription factors that have
been shown to regulate multiple biological processes, such as hematopoiesis …

Background Products of the SOX gene family play important roles in the life process. One of
the members, SOX7, is associated with the development of a variety of cancers as a tumor …