Association between serum FGF21 level and sarcopenia in older adults

HW Jung, JH Park, DA Kim, IY Jang, SJ Park, JY Lee… - Bone, 2021 - Elsevier
Background With emerging basic research evidence suggesting that fibroblast growth factor
(FGF) 21 is a catabolic molecule on muscle metabolism, we aimed to analyze the serum …

Association of plasma FGF21 levels with muscle mass and muscle strength in a national multicentre cohort study: Korean Frailty and Aging Cohort Study

E Roh, SY Hwang, HJ Yoo, SH Baik, B Cho… - Age and …, 2021 - academic.oup.com
Background despite of the beneficial effects of fibroblast growth factor (FGF) 21 in several
metabolic diseases, the association of plasma FGF21 with muscle mass and muscle …

Association of FGF19 and FGF21 levels with primary sarcopenia

R Bag Soytas, V Suzan, P Arman… - Geriatrics & …, 2021 - Wiley Online Library
Aim Serum fibroblast growth factor (FGF)19 and FGF21 levels have been reported to be
associated with muscle hemostasis. This study aims to explore the relationship between the …

Longitudinal measurements of FGF23, sarcopenia, frailty and fracture in older community dwelling women

L Egund, TK Paulin, H Ekstubbe, P Bartosch… - The Journal of Frailty & …, 2023 - Springer
Background FGF23 has been associated with frailty and functional performance in older
individuals, but the association to sarcopenia is unknown. Objectives To investigate the …

[HTML][HTML] Circulating levels of fibroblast growth factor-21 increase with age independently of body composition indices among healthy individuals

LJ Hanks, OM Gutiérrez, MM Bamman, A Ashraf… - Journal of clinical & …, 2015 - Elsevier
Background Circulating FGF21 levels are commonly elevated in disease states. There is
limited information regarding concentrations of circulating FGF21 in the absence of disease …

Fibroblast growth factor-21 is induced in human skeletal muscles by hyperinsulinemia

P Hojman, M Pedersen, AR Nielsen… - Diabetes, 2009 - Am Diabetes Assoc
OBJECTIVE Fibroblast growth factor-21 (FGF-21) is a potent metabolic regulator, which in
animal models has been shown to improve glucose metabolism and insulin sensitivity …

Effects of insulin and exercise training on FGF21, its receptors and target genes in obesity and type 2 diabetes

R Kruse, SG Vienberg, BF Vind, B Andersen, K Højlund - Diabetologia, 2017 - Springer
Aims/hypothesis Pharmacological doses of FGF21 improve glucose tolerance, lipid
metabolism and energy expenditure in rodents. Induced expression and secretion of FGF21 …

Serum FGF21 levels are altered by various factors including lifestyle behaviors in male subjects

K Nakanishi, C Ishibashi, S Ide, R Yamamoto… - Scientific Reports, 2021 - nature.com
Fibroblast growth factor (FGF) 21 has various functions, including glucose and lipid
metabolism. This cross-sectional study aimed to investigate specific conditions that might …

Fibroblast growth factor 21 (FGF21) and bone: is there a relationship in humans?

P Lee, J Linderman, S Smith, RJ Brychta… - Osteoporosis …, 2013 - Springer
In animals, high fibroblast growth factor 21 (FGF21) states improve insulin resistance but
induce bone loss. Whether FGF21 relates to bone mineral density (BMD) is unknown in …

Daily physical activity, fasting glucose, uric acid, and body mass index are independent factors associated with serum fibroblast growth factor 21 levels

D Cuevas-Ramos, P Almeda-Valdes… - European journal of …, 2010 - academic.oup.com
Objective Fibroblast growth factor 21 (FGF21) levels have been linked with beneficial effects
on glucose and lipid metabolism in animals. It is elevated in humans with the metabolic …