Nowadays, liver cancer, cirrhosis and other liverrelated diseases are the fifth most common
cause of mortality in the UK. Furthermore, chronic liver diseases (CLDs) are one of the major …

Angiogenesis is a dynamic, hypoxia-stimulated and growth factor-dependent process, and is
currently referred to as the formation of new vessels from pre-existing blood vessels …

Recent data indicate that hepatic angiogenesis, regardless of the etiology, takes place in
chronic liver diseases (CLDs) that are characterized by inflammation and progressive …

Angiogenesis and disruption of liver vascular architecture have been linked to progression
to cirrhosis and liver cancer (HCC) in chronic liver diseases, which contributes both to …

Pathologic angiogenesis appears to be intrinsically associated with the fibrogenic
progression of chronic liver diseases, which eventually leads to the development of cirrhosis …

Introduction: Persistent inflammation and hypoxia are strong stimulus for pathological
angiogenesis and vascular remodeling, and are also the most important elements resulting …

Angiogenesis is a dynamic, hypoxiastimulated and growth factor-dependent process,
eventually leading to the formation of new vessels from pre-existing blood vessels. In the last …

With more than half a million new cases each year, hepatocellular carcinoma (HCC) is the
fifth most common tumor worldwide and the third cause of cancer-related deaths [1]. At the …

Liver fibrosis affects over 100 million people in the world; it represents a multifactorial, fibro-
inflammatory disorder characterized by exacerbated production of extracellular matrix with …

Intrahepatic hypoxia may occur during the inflammatory and fibrotic processes that
characterize several chronic liver diseases of viral and autoimmune origin. As a …