Surface functionalization of gold nanoparticles for targeting the tumor microenvironment to improve antitumor efficiency

KF Tan, LLA In, P Vijayaraj Kumar - ACS applied bio materials, 2023 - ACS Publications
Gold nanoparticles (AuNPs) have undergone significant research for their use in the
treatment of cancer. Numerous researchers have established their potent antitumor …

Gold nanoparticle surface functionalization: A necessary requirement in the development of novel nanotherapeutics

JR Nicol, D Dixon, JA Coulter - Nanomedicine, 2015 - Taylor & Francis
With several gold nanoparticle-based therapies currently undergoing clinical trials, these
treatments may soon be in the clinic as novel anticancer agents. Gold nanoparticles are the …

[HTML][HTML] Gold nanoparticles in cancer theranostics

Q Gao, J Zhang, J Gao, Z Zhang, H Zhu… - … in bioengineering and …, 2021 - frontiersin.org
Conventional cancer treatments, such as surgical resection, radiotherapy, and
chemotherapy, have achieved significant progress in cancer therapy. Nevertheless, some …

[HTML][HTML] Gold nanoparticles: construction for drug delivery and application in cancer immunotherapy

H Huang, R Liu, J Yang, J Dai, S Fan, J Pi, Y Wei… - Pharmaceutics, 2023 - mdpi.com
Cancer immunotherapy is an innovative treatment strategy to enhance the ability of the
immune system to recognize and eliminate cancer cells. However, dose limitations, low …

[HTML][HTML] Application of gold nanoparticle-based materials in cancer therapy and diagnostics

AA Vodyashkin, MGH Rizk, P Kezimana, AA Kirichuk… - ChemEngineering, 2021 - mdpi.com
Several metal nanoparticles have been developed for medical application. While all have
their benefits, gold nanoparticles (AuNPs) are ideal in cancer therapy and diagnosis as they …

Size-and surface chemistry-dependent pharmacokinetics and tumor accumulation of engineered gold nanoparticles after intravenous administration

J Wang, R Bai, R Yang, J Liu, J Tang, Y Liu, J Li… - Metallomics, 2015 - academic.oup.com
Engineered gold nanoparticles (AuNPs) have recently drawn an increased interest in
disease diagnostics and therapies. However, reports on detailed studies of AuNPs …

[HTML][HTML] Off to the organelles-killing cancer cells with targeted gold nanoparticles

M Kodiha, YM Wang, E Hutter, D Maysinger… - Theranostics, 2015 - ncbi.nlm.nih.gov
Gold nanoparticles (AuNPs) are excellent tools for cancer cell imaging and basic research.
However, they have yet to reach their full potential in the clinic. At present, we are only …

Gold nanoparticle-based drug delivery platform for antineoplastic chemotherapy

JJ Liang, YY Zhou, J Wu, Y Ding - Current drug metabolism, 2014 - ingentaconnect.com
Gold nanoparticles (AuNPs) have demonstrated increasingly wide applications in drug
delivery due to their unique physicochemical and optical properties as well as low toxicity …

Gold nanoparticles for the delivery of cancer therapeutics

DM Connor, AM Broome - Advances in Cancer Research, 2018 - Elsevier
Abstract Gold nanoparticles (Au NPs) are very attractive and versatile nanoparticles since
they have a remarkable capacity to absorb and scatter light, convert optical energy into heat …

Application of gold nanoparticles for targeted therapy in cancer

CR Patra, R Bhattacharya… - Journal of …, 2008 - ingentaconnect.com
Cancer is a major public health problem worldwide. Some of the key challenges in cancer
are early detection, diagnosis, and targeted therapy. Most of the patients are usually …