Bioinformatics and translation initiation

X Xia, X Xia - Bioinformatics and the Cell: Modern Computational …, 2018 - Springer
Translation consists of three subprocesses: initiation, elongation, and termination, all
involving signal motifs and their decoders. Shine-Dalgarno (SD) sequences in prokaryotic …

The diversity of Shine-Dalgarno sequences sheds light on the evolution of translation initiation

JD Wen, ST Kuo, HHD Chou - RNA biology, 2021 - Taylor & Francis
ABSTRACT Shine-Dalgarno (SD) sequences, the core element of prokaryotic ribosome-
binding sites, facilitate mRNA translation by base-pair interaction with the anti-SD (aSD) …

Comparative genomic analysis of translation initiation mechanisms for genes lacking the Shine–Dalgarno sequence in prokaryotes

S Nakagawa, Y Niimura, T Gojobori - Nucleic Acids Research, 2017 - academic.oup.com
In prokaryotes, translation initiation is believed to occur through an interaction between the
3΄ tail of a 16S rRNA and a corresponding Shine–Dalgarno (SD) sequence in the 5΄ …

In silico analysis of 5′-UTRs highlights the prevalence of Shine–Dalgarno and leaderless-dependent mechanisms of translation initiation in bacteria and archaea …

A Srivastava, P Gogoi, B Deka, S Goswami… - Journal of Theoretical …, 2016 - Elsevier
In prokaryotes, a heterogeneous set of protein translation initiation mechanisms such as
Shine–Dalgarno (SD) sequence-dependent, SD sequence-independent or ribosomal …

Comparative analysis of base correlations in 5′ untranslated regions of various species

Y Osada, R Saito, M Tomita - Gene, 2006 - Elsevier
Translational initiation signals, such as Shine-Dalgarno (SD) sequences in bacteria and
Kozak consensus sequences in vertebrates, direct ribosomes to initiate protein synthesis …

Translation initiation: variations in the mechanism can be anticipated

N Malys, JEG McCarthy - Cellular and molecular life sciences, 2011 - Springer
Translation initiation is a critical step in protein synthesis. Previously, two major mechanisms
of initiation were considered as essential: prokaryotic, based on SD interaction; and …

The frequency of internal Shine–Dalgarno-like motifs in prokaryotes

GD Diwan, D Agashe - Genome biology and evolution, 2016 - academic.oup.com
In prokaryotes, translation initiation typically depends on complementary binding between a
G-rich Shine–Dalgarno (SD) motif in the 5′ untranslated region of mRNAs, and the 3′ tail …

Dynamic evolution of translation initiation mechanisms in prokaryotes

S Nakagawa, Y Niimura, K Miura… - Proceedings of the …, 2010 - National Acad Sciences
It is generally believed that prokaryotic translation is initiated by the interaction between the
Shine-Dalgarno (SD) sequence in the 5′ UTR of an mRNA and the anti-SD sequence in …

[HTML][HTML] Unraveling the plasticity of translation initiation in prokaryotes: Beyond the invariant Shine-Dalgarno sequence

K Estrada, A Garciarrubio, E Merino - Plos one, 2024 - journals.plos.org
Translation initiation in prokaryotes is mainly defined, although not exclusively, by the
interaction between the anti-Shine-Dalgarno sequence (antiSD), located at the 3'-terminus …

[HTML][HTML] Local absence of secondary structure permits translation of mRNAs that lack ribosome-binding sites

LB Scharff, L Childs, D Walther, R Bock - PLoS genetics, 2011 - journals.plos.org
The initiation of translation is a fundamental and highly regulated process in gene
expression. Translation initiation in prokaryotic systems usually requires interaction between …