Emergent properties of neural repair: elemental biology to therapeutic concepts

ST Carmichael - Annals of neurology, 2016 - Wiley Online Library
Stroke is the leading cause of adult disability. The past decade has seen advances in basic
science research of neural repair in stroke. The brain forms new connections after stroke …

Translating the frontiers of brain repair to treatments: starting not to break the rules

ST Carmichael - Neurobiology of disease, 2010 - Elsevier
The field of neural repair in stroke has identified cellular systems of reorganization and
possible molecular mechanisms. Conceptual barriers now limit the generation of clinically …

Translating concepts of neural repair after stroke: Structural and functional targets for recovery

RW Regenhardt, H Takase, EH Lo… - Restorative neurology …, 2020 - content.iospress.com
Stroke is among the most common causes of adult disability worldwide, and its disease
burden is shifting towards that of a long-term condition. Therefore, the development of …

Cellular and molecular mechanisms of neural repair after stroke: making waves

ST Carmichael - Annals of Neurology: Official Journal of the …, 2006 - Wiley Online Library
Stroke is associated with a limited degree of functional recovery. Imaging studies in humans
have shown that reorganization in periinfarct and connected cortical areas most closely …

Targets for neural repair therapies after stroke

ST Carmichael - Stroke, 2010 - Am Heart Assoc
Studies of neural repair after stroke have developed from a relatively small number of
laboratories doing highly creative discovery science to a field in which reproducible …

Neurorepair versus neuroprotection in stroke

O Hurtado, JM Pradillo, D Alonso-Escolano… - Cerebrovascular …, 2006 - karger.com
Stroke is the second to third leading cause of death and the main cause of severe, long-term
disability in adults. However, treatment is almost reduced to fibrinolysis, a therapy useful in a …

Neurorestorative therapies for stroke: underlying mechanisms and translation to the clinic

ZG Zhang, M Chopp - The lancet neurology, 2009 - thelancet.com
Restorative cell-based and pharmacological therapies for experimental stroke substantially
improve functional outcome. These therapies target several types of parenchymal cells …

Themes and strategies for studying the biology of stroke recovery in the poststroke epoch

ST Carmichael - Stroke, 2008 - Am Heart Assoc
Background and Purpose—This review will focus on the emerging principles of neural repair
after stroke, and on the overlap between cellular mechanisms of neural repair in stroke and …

[HTML][HTML] Enhancing endogenous capacity to repair a stroke-damaged brain: An evolving field for stroke research

LR Zhao, A Willing - Progress in neurobiology, 2018 - Elsevier
Stroke represents a severe medical condition that causes stroke survivors to suffer from long-
term and even lifelong disability. Over the past several decades, a vast majority of stroke …

Neurorestoration after stroke

TD Azad, A Veeravagu, GK Steinberg - Neurosurgical focus, 2016 - thejns.org
Recent advancements in stem cell biology and neuromodulation have ushered in a battery
of new neurorestorative therapies for ischemic stroke. While the understanding of stroke …