Which genes and gene signaling pathways mediate regenerative processes? In recent
years, multiple studies, using a variety of animal models, have aimed to answer this …

In their Review1, Sánchez Alvarado and Tsonis present an interesting discussion of “… the
model systems that are currently used to dissect the molecular and cellular bases of …

The ability to regenerate is scattered among the metazoan tree of life. Further still,
regenerative capacity varies widely within these specific organisms. Numerous organisms …

Background Echinoderms are emerging as important models in regenerative biology.
Significant amount of data are available on cellular mechanisms of post-traumatic repair in …

The potential for regenerating tissues, organs and body parts, even the ability to reconstruct
virtually a complete animal from a body fragment, is expressed to a maximum extent in …

Reparative regeneration is defined as the replacement of lost adult body parts and is a
phenomenon widespread yet highly variable among animals. This raises the question of …

The regenerative potential is expressed to a maximum extent in echinoderms and ascidians.
They provide unique and valuable deuterostome models, closely related to vertebrates (man …

The diversity of regenerative phenomena seen in adult metazoans, as well as their
underlying mechanistic bases, are still far from being comprehensively understood …

Medusozoans, the Cnidarian subphylum, have multiple life stages including sessile polyps
and free-swimming medusae or jellyfish, which are typically bell-shaped gelatinous …

Echinoderms comprise a group of animals with impressive regenerative capabilities. They
can replace complex internal organs following injury or autotomy. In holothurians or sea …