[HTML][HTML] WNT/β-catenin signaling in the development of liver cancers

S He, S Tang - Biomedicine & pharmacotherapy, 2020 - Elsevier
The WNT/β-catenin signaling pathway is a highly conserved and tightly controlled molecular
mechanism that regulates embryonic development, cellular proliferation and differentiation …

Wnt/β-catenin pathway in hepatocellular carcinoma pathogenesis and liver physiology

C Cavard, S Colnot, V Audard, S Benhamouche… - Future …, 2008 - Taylor & Francis
The Wnt/β-catenin pathway is a key developmental pathway for which alterations have been
described in various human cancers. The aberrant activation of this pathway is a major …

Wnt–β-catenin signalling in liver development, health and disease

MJ Perugorria, P Olaizola, I Labiano… - Nature reviews …, 2019 - nature.com
The canonical Wnt–β-catenin pathway is a complex, evolutionarily conserved signalling
mechanism that regulates fundamental physiological and pathological processes. Wnt–β …

Wnt signaling in liver cancer

Y Takigawa, A Brown - Current drug targets, 2008 - ingentaconnect.com
Hepatocellular carcinoma (HCC) is a major cause of cancer death worldwide. As in many
other types of cancer, aberrant activation of the canonical Wnt/β-catenin signaling pathway …

Wnt/β-catenin signaling in liver cancers

W Wang, R Smits, H Hao, C He - Cancers, 2019 - mdpi.com
Liver cancer is among the leading global healthcare issues associated with high morbidity
and mortality. Liver cancer consists of hepatocellular carcinoma (HCC), cholangiocarcinoma …

Role of Wnt/β-catenin signaling in liver metabolism and cancer

SPS Monga - The international journal of biochemistry & cell biology, 2011 - Elsevier
Wnt/β-catenin signaling is known for its role in embryogenesis as well as carcinogenesis. In
the liver, it plays many critical roles during hepatic development and regeneration, and its …

[HTML][HTML] Wnt signaling and hepatocarcinogenesis: molecular targets for the development of innovative anticancer drugs

F Pez, A Lopez, M Kim, JR Wands, CC de Fromentel… - Journal of …, 2013 - Elsevier
Hepatocellular carcinoma (HCC) is one of the most common causes of cancer death
worldwide. HCC can be cured by radical therapies if early diagnosis is done while the tumor …

The Wnt/β-catenin pathway as a therapeutic target in human hepatocellular carcinoma

R Dahmani, PA Just, C Perret - Clinics and research in hepatology and …, 2011 - Elsevier
Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related death
worldwide. However, targeted therapies are still at their beginning for the treatment of this …

The Wnt/β-catenin signaling pathway in liver biology and disease

J Behari - Expert review of gastroenterology & hepatology, 2010 - Taylor & Francis
The Wnt signaling pathway is an evolutionarily conserved, highly complex signaling
pathway that is critical for development, differentiation and cellular homeostasis. The protein …

Wnt/β-catenin signaling as a driver of hepatocellular carcinoma progression: an emphasis on molecular pathways

M Deldar Abad Paskeh, S Mirzaei… - Journal of …, 2021 - Taylor & Francis
Liver cancers cause a high rate of death worldwide and hepatocellular carcinoma (HCC) is
considered as the most common primary liver cancer. HCC remains a challenging disease …