Using artificial intelligence to find the optimal margin width in hepatectomy for colorectal cancer liver metastases

D Bertsimas, GA Margonis, S Sujichantararat… - JAMA …, 2022 - jamanetwork.com
Importance In patients with resectable colorectal cancer liver metastases (CRLM), the choice
of surgical technique and resection margin are the only variables that are under the …

Margin status is still an important prognostic factor in hepatectomies for colorectal liver metastases: a propensity score matching analysis

R Memeo, V De Blasi, R Adam, D Goéré… - World journal of …, 2018 - Wiley Online Library
Objective The width of resection margin is still a matter of debate in case of colorectal liver
metastasis resection. The aim of this study was to determine the risk factors for R1 resection …

Impact of resection margins for colorectal liver metastases in laparoscopic and open liver resection: a propensity score analysis

D Martínez-Cecilia, DA Wicherts, F Cipriani… - Surgical …, 2021 - Springer
Background There is no clear consensus over the optimal width of resection margin for
colorectal liver metastases (CRLM), with evolving definitions alongside the advances on the …

Impact of subcentimeter margin on outcome after hepatic resection for colorectal metastases: a meta-regression approach

A Cucchetti, G Ercolani, M Cescon, E Bigonzi, E Peri… - Surgery, 2012 - Elsevier
BACKGROUND: The optimal margin width and its influence on outcomes after hepatic
resection for colorectal liver metastases is still controversial: a meta-analysis was conducted …

Higher tumor burden neutralizes negative margin status in hepatectomy for colorectal cancer liver metastasis

M Oshi, GA Margonis, Y Sawada, N Andreatos… - Annals of surgical …, 2019 - Springer
Objective The aim of this study was to examine if the prognostic significance of margin status
in hepatectomy for colorectal cancer liver metastasis (CRLM) varies for different levels of …

Surgical margins during hepatic surgery for colorectal liver metastases: complete resection not millimeters defines outcome

TM Pawlik, JN Vauthey - Annals of surgical oncology, 2008 - Springer
Several recent studies have indicated that a margin less than 1 cm is not a contraindication
to resection of colorectal liver metastases (CLM). 1–3 In the one study 2 that appropriately …

Negative surgical margin improved long-term survival of colorectal cancer liver metastases after hepatic resection: a systematic review and meta-analysis

W Liu, Y Sun, L Zhang, BC Xing - International journal of colorectal …, 2015 - Springer
Objective The need to achieve a tumor-free margin of≥ 1 mm (R0) for colorectal liver
metastases (CRLM) after hepatic resection has been questioned recently. This study …

Influence of margins on overall survival after hepatic resection for colorectal metastasis: a meta-analysis

M Dhir, ER Lyden, A Wang, LM Smith, F Ullrich… - Annals of …, 2011 - journals.lww.com
Objective: The aim of our study was to conduct a meta-analysis of reports published on
hepatic resection for colorectal liver metastasis (CRLM) and determine whether a negative …

Impact of surgical margin width on recurrence and overall survival following R0 hepatic resection of colorectal metastases: a systematic review and meta-analysis

GA Margonis, TN Sergentanis… - Annals of …, 2018 - journals.lww.com
Objective: To examine the impact of surgical margin width on survival following R0 hepatic
resection for colorectal metastases (CRLM). Summary of Background Data: Although …

Resection margin and survival in 2368 patients undergoing hepatic resection for metastatic colorectal cancer: surgical technique or biologic surrogate?

E Sadot, BG Koerkamp, JN Leal, J Shia… - Annals of …, 2015 - journals.lww.com
Objectives: The impact of margin width on overall survival (OS) in the context of other
prognostic factors after resection for colorectal liver metastases is unclear. We evaluated the …