Imaging of Tauopathies with PET Ligands: State of the Art and Future Outlook
M Conte, MS De Feo, MMA Sidrak, F Corica, J Gorica… - Diagnostics, 2023 - mdpi.com
(1) Background: Tauopathies are a group of diseases characterized by the deposition of
abnormal tau protein. They are distinguished into 3R, 4R, and 3R/4R tauopathies and also …
abnormal tau protein. They are distinguished into 3R, 4R, and 3R/4R tauopathies and also …
Tau imaging in neurodegenerative diseases using positron emission tomography
Abstract Purpose of Review Abnormal accumulation of tau protein is the main hallmark of
tauopathies and is closely associated with neurodegeneration and cognitive impairment …
tauopathies and is closely associated with neurodegeneration and cognitive impairment …
The tauopathies: Neuroimaging characteristics and emerging experimental therapies
KJ Riley, BD Graner, MC Veronesi - Journal of Neuroimaging, 2022 - Wiley Online Library
The tauopathies are a heterogeneous group of neurodegenerative disorders in which the
prevailing underlying disease process is intracellular deposition of abnormal misfolded tau …
prevailing underlying disease process is intracellular deposition of abnormal misfolded tau …
Tau imaging with PET: an overview of challenges, current progress, and future applications.
JS Robertson, CC Rowe… - The Quarterly Journal of …, 2017 - europepmc.org
Folded and misfolded tau is common to many neurodegenerative conditions, collectively
termed" tauopathies". In recent years, many efforts have contributed toward development of …
termed" tauopathies". In recent years, many efforts have contributed toward development of …
Development of tau PET imaging ligands and their utility in preclinical and clinical studies
The pathological features of Alzheimer's disease are senile plaques which are aggregates
of β-amyloid peptides and neurofibrillary tangles in the brain. Neurofibrillary tangles are …
of β-amyloid peptides and neurofibrillary tangles in the brain. Neurofibrillary tangles are …
[PDF][PDF] Tau positron emission tomography in tauopathies: A narrative review
H Lee, Y Gu, SW Seo, SH Moon - Precision and Future Medicine, 2023 - pfmjournal.org
Aggregation of misfolded tau in the brain is a major pathological feature common in various
neurodegenerative disorders known as tauopathies, including Alzheimer's disease …
neurodegenerative disorders known as tauopathies, including Alzheimer's disease …
Tau PET and tauopathies
K Herholz - European Journal of Nuclear Medicine and Molecular …, 2016 - Springer
PET tracers for pathological deposits of tau protein aggregates in the brain are currently
undergoing rapid development. They are targeting pathological deposits of tau aggregates …
undergoing rapid development. They are targeting pathological deposits of tau aggregates …
[引用][C] [ICP178]: HEADTOHEAD IN VIVO COMPARISON OF TAUSPECIFIC PET TRACERS IN ALZHEIMER's DISEASE: [11C]THK5351 VERSUS [11C]PBB3 …
K Chiotis, P Stenkrona, O Almkvist… - Alzheimer's & …, 2017 - Wiley Online Library
Background During the past five years, the development of tau-specific PET tracers has
enabled the visualization of tau deposits in Alzheimer's disease (AD) as well as other …
enabled the visualization of tau deposits in Alzheimer's disease (AD) as well as other …
Disclosing tau tangles using PET imaging: a pharmacological review of the radiotracers available in 2021
É Van Wambeke, T Gérard, R Lhommel… - Acta Neurologica …, 2022 - Springer
Neurological symptoms depend on the topography of the lesions in the nervous system,
hence the importance of brain imaging for neurologists. Neurological treatment, however …
hence the importance of brain imaging for neurologists. Neurological treatment, however …
The development and validation of tau PET tracers: current status and future directions
N Okamura, R Harada, A Ishiki, A Kikuchi… - Clinical and translational …, 2018 - Springer
Purpose To provide an overview on positron emission tomography (PET) imaging of tau
pathology in Alzheimer's disease (AD) and other neurodegenerative disorders. Results …
pathology in Alzheimer's disease (AD) and other neurodegenerative disorders. Results …