In postmortem investigations of patients with dementia of Alzheimer type (AD/SDAT)(n= 14)
the brain weight was significantly reduced when compared to controls (n= 16). In four …

The concentrations of monoamines and cholineacetyl transferase (CAT) are reduced in
brains from patients with normal aging. According to findings about the dopamine (DA) …

Dementia can be defined as a progressive loss of cognitive and other" higher" intellectual
functions as a result of organic brain disease. There are many causes of dementia: some of …

The association of dementia in the elderly with microscopic pathological abnormalities in the
cerebral cortex was originally made by Alzheimer (1907). Modern commentators prefer not …

Monoamine metabolism in senile dementia of the Alzheimer-type (SDAT) was assessed by
measuring the concentrations of the dopamine metabolite HVA, the noradrenaline …

The integrity of cholinergic and monoaminergic neuronal systems in Alzheimer-type
dementia (ATD) was studied using a combination of morphological and biochemical …

The possible involvement of dopaminergic neurons in dementia of Alzheimer type
(AD/SDAT) was studied in autopsied brains from 20 patients with AD/SDAT. Dopamine (DA) …

Alzheimer's disease (AD) and senile dementia (SD) are often classified together, but there
are genetic, biochemical, neuropathological and clinical arguments for separating them. The …

Choline acetyltransferase (ChAT) activity and acetylcholinesterase (AChE) staining were
examined in different cortical regions, hippocampal formation and basal forebrain of non …

Reductions of the levels of transmitter substances and of the activities of enzymes involved
in their synthesis have been demonstrated in the aging brain. The sensitivity to the aging …