Antagonists of growth hormone-releasing hormone inhibit the growth of pituitary adenoma cells by hampering oncogenic pathways and promoting apoptotic signaling
I Gesmundo, G Granato, AC Fuentes-Fayos… - Cancers, 2021 - mdpi.com
Simple Summary Many studies have demonstrated that the antagonists of growth hormone-
releasing hormone (GHRH) exert inhibitory activities in a variety of experimental cancers; …
releasing hormone (GHRH) exert inhibitory activities in a variety of experimental cancers; …
Inhibitory effects of antagonists of growth hormone-releasing hormone (GHRH) in thyroid cancer
Growth hormone-releasing hormone (GHRH) is a peptide hormone secreted by the
hypothalamus that regulates the synthesis and secretion of growth hormone (GH) in the …
hypothalamus that regulates the synthesis and secretion of growth hormone (GH) in the …
Endocrine and antineoplastic actions of growth hormone-releasing hormone antagonists
M Kovacs, AV Schally, JL Varga… - Current medicinal …, 2008 - ingentaconnect.com
Potent antagonists of growth hormone-releasing hormone (GHRH) have been developed for
the treatment of disorders caused by excessive GHRH or growth hormone (GH) production …
the treatment of disorders caused by excessive GHRH or growth hormone (GH) production …
Antagonists of growth-hormone-releasing hormone: an emerging new therapy for cancer
AV Schally, JL Varga, JB Engel - Nature Clinical Practice Endocrinology …, 2008 - nature.com
This article reviews the potential clinical uses of antagonists of growth-hormone-releasing
hormone (GHRH) for tumor therapy. GHRH antagonists suppress the growth of various …
hormone (GHRH) for tumor therapy. GHRH antagonists suppress the growth of various …
[HTML][HTML] Growth hormone-releasing hormone (GHRH) and its agonists inhibit hepatic and tumoral secretion of IGF-1
T Cui, AV Schally - Oncotarget, 2018 - ncbi.nlm.nih.gov
The role of hypothalamic growth hormone-releasing hormone (GHRH) in the release of
growth hormone (GH) from the pituitary is well established. However, direct effects of GHRH …
growth hormone (GH) from the pituitary is well established. However, direct effects of GHRH …
Growth hormone-releasing hormone antagonists inhibit growth of human ovarian cancer
A Papadia, AV Schally, G Halmos… - Hormone and …, 2011 - thieme-connect.com
Epithelial ovarian carcinoma is the leading cause of cancer-related deaths among women
with gynecologic malignancies. Antagonists of the growth hormone-releasing hormone …
with gynecologic malignancies. Antagonists of the growth hormone-releasing hormone …
Antagonists of growth hormonereleasing hormone inhibit the proliferation of human benign prostatic hyperplasia cells
A Siejka, AV Schally, NL Block, N Barabutis - The Prostate, 2010 - Wiley Online Library
BACKGROUND Growth hormonereleasing hormone (GHRH), besides stimulating the
secretion of GH from the pituitary gland, acts as an autocrine/paracrine growth factor in many …
secretion of GH from the pituitary gland, acts as an autocrine/paracrine growth factor in many …
Inhibitory effects of GHRH antagonists on human GH-secreting adenoma tissue
L Szalontay, RJ Benveniste, AV Schally, I Vidaurre… - …, 2012 - karger.com
Experimental data indicate that antagonists of growth hormone-releasing hormone (GHRH)
could be used clinically in disorders characterized by excessive GHRH/growth hormone …
could be used clinically in disorders characterized by excessive GHRH/growth hormone …
Antagonists of Growth Hormone–Releasing Hormone (GHRH) in Cancer
JL Varga, AV Schally - Handbook of Biologically Active Peptides, 2006 - Elsevier
In the past 10 years potent antagonistic analogs of growth hormone-releasing hormone (GH-
RH) have been synthesized. These GH-RH antagonists bind to pituitary receptors for GH-RH …
RH) have been synthesized. These GH-RH antagonists bind to pituitary receptors for GH-RH …
Effects of growth hormone-releasing hormone and its agonistic and antagonistic analogs in cancer and non-cancerous cell lines
N Barabutis, A Siejka… - … journal of oncology, 2010 - spandidos-publications.com
The neuropeptide growth hormone-releasing hormone (GHRH) is secreted by the
hypothalamus and upon the binding to the receptors for GHRH on the pituitary gland …
hypothalamus and upon the binding to the receptors for GHRH on the pituitary gland …