Medical pain management is in crisis; from the pervasiveness of pain to inadequate pain
treatment, from the escalation of prescription opioids to an epidemic in addiction, diversion …

The treatment of noncancer pain in the United States and globally is met with significant
challenges, resulting in profound physical, emotional, and societal costs. Based on this …

Background: Opioid abuse has increased at an alarming rate. However, available evidence
suggests a wide variance in the use of opioids, as documented by different medical …

Background: Opioid abuse has continued to increase at an alarming rate since our last
opioid guidelines were published in 2005. Available evidence suggests a continued wide …

Background: Opioid use, abuse, and adverse consequences, including death, have
escalated at an alarming rate since the 1990s. In an attempt to control opioid abuse …

Each year, $100 billion is spent on pain care, yet 40% of Americans experience daily pain,
including 50 million people with chronic pain and 25 million people with acute pain. The …

Pain is ubiquitous. At some point in time it affects everyone. For many millions pain becomes
chronic, a scourge that impacts every facet of life—work, hobbies, family relations, social …

Chronic pain exerts a tremendous burden on individuals and societies. If one views chronic
pain as a single disease entity, then it is the most common and costly medical condition. At …

Despite the availability of effective pain treatments, there are numerous barriers to effective
management resulting in a large proportion of patients not achieving optimal pain control …

Background Pain can significantly influence an individual's health status and can have
serious negative consequences: poor nutrition, decreased appetite, abnormal sleep …