Potential of therapeutic small molecules in apoptosis regulation in the treatment of neurodegenerative diseases: An updated review
HG Dailah - Molecules, 2022 - mdpi.com
Neurodegenerative disorders (NDs) include Parkinson's disease (PD), Alzheimer's disease
(AD), Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS) and the common …
(AD), Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS) and the common …
Treating neurodegenerative conditions through the understanding of neuronal apoptosis
SR D'Mello, PC Chin - Current Drug Targets-CNS & …, 2005 - ingentaconnect.com
Neurological diseases disrupt the quality of the lives of patients and often leads to their
premature deaths. A common feature of most neurological diseases is the degeneration of …
premature deaths. A common feature of most neurological diseases is the degeneration of …
Matter of life and death: the pharmacological approaches targeting apoptosis in brain diseases
V Cavallucci, M D'Amelio - Current pharmaceutical design, 2011 - ingentaconnect.com
Neurodegenerative diseases that include amyotrophic lateral sclerosis, Huntington's
disease, Alzheimer's disease, Parkinson's disease, stroke, brain trauma and spinal cord …
disease, Alzheimer's disease, Parkinson's disease, stroke, brain trauma and spinal cord …
Antiapoptotic drugs: a therapautic strategy for the prevention of neurodegenerative diseases
FX Sureda, F Junyent, E Verdaguer… - Current …, 2011 - ingentaconnect.com
The purpose of this review is to discuss potential pathways involved in the pathogenesis of
neurodegenerative diseases, highlighting current pharmacological drug targets in neuronal …
neurodegenerative diseases, highlighting current pharmacological drug targets in neuronal …
Cell death targets and potential modulators in Alzheimer's disease
RE Castro, M MM Santos, P MC Gloria… - Current …, 2010 - ingentaconnect.com
Apoptosis is now recognized as a normal feature in the development of the nervous system
and may also play a role in neurodegenerative disorders, such as Alzheimer's disease. Cell …
and may also play a role in neurodegenerative disorders, such as Alzheimer's disease. Cell …
Apoptotic mechanisms involved in neurodegenerative diseases: experimental and therapeutic approaches.
Alzheimer's disease (AD) and Parkinson's disease (PD) are two of the most significant
neurodegenerative disorders in the developed world. However, although these diseases …
neurodegenerative disorders in the developed world. However, although these diseases …
Apoptosis and its therapeutic implications in neurodegenerative diseases
NS Erekat - Clinical Anatomy, 2022 - Wiley Online Library
Neurodegenerative disorders are characterized by progressive loss of particular populations
of neurons. Apoptosis has been implicated in the pathogenesis of neurodegenerative …
of neurons. Apoptosis has been implicated in the pathogenesis of neurodegenerative …
Inhibition of ataxia telangiectasia-p53-E2F-1 pathway in neurons as a target for the prevention of neuronal apoptosis
Over the last few decades, understanding of the mechanisms involved in the process of
neuronal cell death has grown. Recent findings have established that DNA damage, and …
neuronal cell death has grown. Recent findings have established that DNA damage, and …
Cell death, inflammation and oxidative stress in neurodegenerative diseases: mechanisms and cytoprotective molecules
A Vejux - International Journal of Molecular Sciences, 2021 - mdpi.com
Neurodegenerative diseases are the most common chronic neurological pathologies
associated with age, with a major impact on the patient's quality of life. These pathologies …
associated with age, with a major impact on the patient's quality of life. These pathologies …
Neuronal apoptosis in neurodegenerative diseases: from basic research to clinical application
In recent years, the investigation of erroneous regulation of apoptotic mechanisms during
acute and chronic injury of neuronal cells has gained increasing attention. Besides acute …
acute and chronic injury of neuronal cells has gained increasing attention. Besides acute …
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