Platelet function testing and implications for clinical practice

JP Collet, G Montalescot - Journal of cardiovascular …, 2009 - journals.sagepub.com
Platelets are key mediators in the pathophysiology of atherothrombotic disease.
Inappropriate platelet activation can lead to thrombosis and ischemic events. Platelet …

Platelet function testing in contemporary clinical and interventional practice

F Franchi, F Rollini, JR Cho, E Ferrante… - … treatment options in …, 2014 - Springer
Opinion statement Dual antiplatelet therapy with a combination of aspirin and an inhibitor of
the ADP P2Y 12 receptor is the recommended treatment for patients with acute coronary …

Platelet function monitoring in patients with coronary artery disease

PA Gurbel, RC Becker, KG Mann, SR Steinhubl… - Journal of the American …, 2007 - jacc.org
Studies focused on patient responsiveness to antiplatelet therapies, particularly aspirin and
clopidogrel, have increased in recent years. However, the relations of in vivo platelet …

Platelet function testing: methods of assessment and clinical utility

D Mylotte, D Foley, D Kenny - Cardiovascular & Hematological …, 2011 - ingentaconnect.com
Platelets play a central role in the regulation of both thrombosis and haemostasis yet tests of
platelet function have, until recently, been exclusively used in the diagnosis and …

Role of platelet function testing in clinical practice: current concepts and future perspectives

D Sibbing, RA Byrne, A Kastrati - Current Drug Targets, 2011 - ingentaconnect.com
Oral antiplatelet therapy is routinely administered to ACS patients as well as to patients
undergoing percutaneous coronary intervention (PCI) with the primary aim of inhibiting …

Platelet function analysis: at the edge of meaning

JH Oestreich, SS Smyth… - Thrombosis and …, 2009 - thieme-connect.com
Anti-platelet agents are a cornerstone in the treatment of symptomatic coronary artery
disease and acute coronary syndromes. Despite the proven benefits of acetylsalicylic acid …

Assessing the current role of platelet function testing

E Braunwald, D Angiolillo, E Bates… - … Indexed and Peer …, 2008 - Wiley Online Library
In vitro platelet function tests are commonly applied in research and offer justification for
using antiplatelet therapy. However, studies assessing the ability of standardized platelet …

Platelet function testing in atherothrombotic disease

E Lerkevang Grove, RF Storey… - Current pharmaceutical …, 2012 - ingentaconnect.com
Platelet function testing was introduced more than a century ago with the invention of
bleeding time; a test which has now been replaced by more accurate methods. Light …

Platelet function testing in patients on antiplatelet medications

L Gross, D Aradi, D Sibbing - Seminars in thrombosis and …, 2016 - thieme-connect.com
Guidelines provide a Class IA recommendation for the use of dual antiplatelet therapy in
patients undergoing percutaneous coronary intervention (PCI). However, there is …

Platelet function testing and cardiovascular outcomes: steps forward in identifying the best predictive measure

DJ Angiolillo, F Alfonso - Thrombosis and haemostasis, 2007 - thieme-connect.com
O ver the past years there has been accumulating evidence on the prognostic value of
platelet function on cardiovascular outcomes (1). In particular, patients who persist with …