The role of acetylcholine in learning and memory

ME Hasselmo - Current opinion in neurobiology, 2006 - Elsevier
Pharmacological data clearly indicate that both muscarinic and nicotinic acetylcholine
receptors have a role in the encoding of new memories. Localized lesions and antagonist …

Acetylcholine and memory

ME Hasselmo, JM Bower - Trends in neurosciences, 1993 - cell.com
Acetylcholine may set the dynamics of cortical networks to those appropriate for learning of
new information, while decreased cholinergic modulation may set the appropriate dynamics …

Acetylcholine modulation of neural systems involved in learning and memory

PE Gold - Neurobiology of learning and memory, 2003 - Elsevier
Extensive evidence supports the view that cholinergic mechanisms modulate learning and
memory formation. This paper reviews evidence for cholinergic regulation of multiple …

Cholinergic modulation of cortical associative memory function

ME Hasselmo, BP Anderson… - Journal of …, 1992 - journals.physiology.org
1. The effect of cholinergic modulation on associative memory function was studied in a
computational model based on the physiology and anatomic structure of piriform cortex …

Acetylcholine and memory: a long, complex and chaotic but still living relationship

J Micheau, A Marighetto - Behavioural brain research, 2011 - Elsevier
Even though “procholinergic” drugs are almost the sole kind of treatments currently used as
cognitive enhancers in patients with Alzheimer's disease, the role of acetylcholine (ACh) in …

Cholinergic modulation of the hippocampal region and memory function

J Haam, JL Yakel - Journal of neurochemistry, 2017 - Wiley Online Library
Acetylcholine (AC h) plays an important role in memory function and has been implicated in
agingrelated dementia, in which the impairment of hippocampusdependent learning …

[HTML][HTML] A specific role for septohippocampal acetylcholine in memory?

A Easton, V Douchamps, M Eacott, C Lever - Neuropsychologia, 2012 - Elsevier
Acetylcholine has long been implicated in memory, including hippocampal-dependent
memory, but the specific role for this neurotransmitter is difficult to identify in human …

[PDF][PDF] Cholinergic modulation of cortical function

ME Hasselmo, LM Giocomo - Journal of Molecular Neuroscience, 2006 - academia.edu
Extensive physiological research has demonstrated a number of common effects of
acetylcholine within cortical structures, including the hippocampus, piriform cortex, and …

The cholinergic system and hippocampal plasticity

BD Drever, G Riedel, B Platt - Behavioural brain research, 2011 - Elsevier
Acetylcholine is an essential excitatory neurotransmitter in the central nervous system and
undertakes a vital role in cognitive function. Consequently, there is ample evidence to …

Encoding and retrieval of episodic memories: role of cholinergic and GABAergic modulation in the hippocampus

ME Hasselmo, BP Wyble, GV Wallenstein - Hippocampus, 1996 - Wiley Online Library
This research focuses on linking episodic memory function to the cellular physiology of
hippocampal neurons, with a particular emphasis on modulatory effects at cholinergic and γ …