Nature achieves differentiation of specific and nonspecific binding in molecular interactions
through precise control of biomolecules in space and time. Artificial systems such as …

Recognition receptors play a key role in the successful implementation of chemical and
biosensors. Molecular recognition refers to non-covalent specific binding between …

Conspectus The biosensor community has long focused on achieving the lowest possible
detection limits, with specificity (the ability to differentiate between closely similar target …

Analytical technologies based on binding assays have evolved substantially since their
inception nearly 60 years ago, but our conceptual understanding of molecular recognition …

This Perspective focuses on the latest strategies and challenges for the development of
bioanalytical sensors with sub-picomolar detection limits. Achieving sub-picomolar detection …

We review recent developments in our understanding of molecular recognition and ligand
association, focusing on two major viewpoints:(a) studies that highlight new physical insight …

Molecular recognition, which is the process of biological macromolecules interacting with
each other or various small molecules with a high specificity and affinity to form a specific …

Biomolecular recognition has long been an important theme in artificial sensing
technologies. A current limitation of protein-and nucleic acid-based recognition, however, is …

Label-free biosensors are devices that use biological or chemical receptors to detect
analytes (molecules) in a sample. They give detailed information on the selectivity, affinity …

Understanding the basic forces that determine molecular recognition helps to elucidate
mechanisms of biological processes and facilitates discovery of innovative biotechnological …