Transcriptomic organization of the human brain in post-traumatic stress disorder
Despite extensive study of the neurobiological correlates of post-traumatic stress disorder
(PTSD), little is known about its molecular determinants. Here, differential gene expression …
(PTSD), little is known about its molecular determinants. Here, differential gene expression …
Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder
Post-traumatic stress disorder (PTSD) genetics are characterized by lower discoverability
than most other psychiatric disorders. The contribution to biological understanding from …
than most other psychiatric disorders. The contribution to biological understanding from …
Genome-wide association study of post-traumatic stress disorder reexperiencing symptoms in> 165,000 US veterans
Post-traumatic stress disorder (PTSD) is a major problem among military veterans and
civilians alike, yet its pathophysiology remains poorly understood. We performed a genome …
civilians alike, yet its pathophysiology remains poorly understood. We performed a genome …
Decoding shared versus divergent transcriptomic signatures across cortico-amygdala circuitry in PTSD and depressive disorders
Objective: Posttraumatic stress disorder (PTSD) is a debilitating neuropsychiatric disease
that is highly comorbid with major depressive disorder (MDD) and bipolar disorder. The …
that is highly comorbid with major depressive disorder (MDD) and bipolar disorder. The …
Genomic approaches to posttraumatic stress disorder: the psychiatric genomic consortium initiative
Posttraumatic stress disorder (PTSD) after exposure to a traumatic event is a highly
prevalent psychiatric disorder. Heritability estimates from twin studies as well as from recent …
prevalent psychiatric disorder. Heritability estimates from twin studies as well as from recent …
[PDF][PDF] Analysis of genetically regulated gene expression identifies a prefrontal PTSD gene, SNRNP35, specific to military cohorts
To reveal post-traumatic stress disorder (PTSD) genetic risk influences on tissue-specific
gene expression, we use brain and non-brain transcriptomic imputation. We impute …
gene expression, we use brain and non-brain transcriptomic imputation. We impute …
Convergent molecular, cellular, and cortical neuroimaging signatures of major depressive disorder
Major depressive disorder emerges from the complex interactions of biological systems that
span genes and molecules through cells, networks, and behavior. Establishing how …
span genes and molecules through cells, networks, and behavior. Establishing how …
[HTML][HTML] Distinct proteomic, transcriptomic, and epigenetic stress responses in dorsal and ventral hippocampus
Background Acutely stressful experiences can trigger neuropsychiatric disorders and impair
cognitive processes by altering hippocampal function. Although the intrinsic organization of …
cognitive processes by altering hippocampal function. Although the intrinsic organization of …
Genetic approaches to understanding post-traumatic stress disorder
Post-traumatic stress disorder (PTSD) is increasingly recognized as both a disorder of
enormous mental health and societal burden, but also as an anxiety disorder that may be …
enormous mental health and societal burden, but also as an anxiety disorder that may be …
The Psychiatric Genomics Consortium Posttraumatic Stress Disorder Workgroup: posttraumatic stress disorder enters the age of large-scale genomic collaboration
MW Logue, AB Amstadter, DG Baker… - …, 2015 - nature.com
The development of posttraumatic stress disorder (PTSD) is influenced by genetic factors.
Although there have been some replicated candidates, the identification of risk variants for …
Although there have been some replicated candidates, the identification of risk variants for …
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