Gut Microbiota—Adversary or Ally? Its Role and Significance in Colorectal Cancer Pathogenesis, Progression, and Treatment

K Chawrylak, M Leśniewska, K Mielniczek, K Sędłak… - Cancers, 2024 - mdpi.com
In 2022, colorectal cancer (CRC) was the third most prevalent malignancy worldwide. The
therapeutic approach for CRC typically involves a multimodal regimen. The human gut …

Gut microbiota in colorectal cancer development and therapy

CC Wong, J Yu - Nature Reviews Clinical Oncology, 2023 - nature.com
Colorectal cancer (CRC) is one of the commonest cancers globally. A unique aspect of CRC
is its intimate association with the gut microbiota, which forms an essential part of the tumour …

Gut microbiota impacts on the efficacy of anticancer treatment of colorectal cancer

J Hong, JY Fang - Microbiome in gastrointestinal cancer, 2023 - Springer
Considering the stubbornly high morbidity and mortality and unsatisfactory clinical treatment
efficacy of colorectal cancer (CRC), it is still urgent for exploring better therapy regimens …

A perspective on the role of microbiome for colorectal cancer treatment

S Kalasabail, J Engelman, LY Zhang, E El-Omar… - Cancers, 2021 - mdpi.com
Simple Summary Colorectal cancer is the third most diagnosed cancer worldwide and
contributes significantly to global mortality and morbidity. The gut microbiome, composed of …

Gut microbiota modulation: a tool for the management of colorectal cancer

Y Wang, H Li - Journal of Translational Medicine, 2022 - Springer
Colorectal cancer (CRC) is the second cause of cancer death and the third most frequently
diagnosed cancer. Besides the lifestyle, genetic and epigenetic alterations, and …

[HTML][HTML] Linking gut microbiota to colorectal cancer

H Raskov, J Burcharth, HC Pommergaard - Journal of cancer, 2017 - ncbi.nlm.nih.gov
Pre-clinical and clinical data produce mounting evidence that the microbiota is strongly
associated with colorectal carcinogenesis. Dysbiosis may change the course of …

Gut microbiota and colorectal cancer: insights into pathogenesis for novel therapeutic strategies

Y Kang, W Pan, Y Cai - Zeitschrift für Gastroenterologie, 2017 - thieme-connect.com
Colorectal cancer (CRC), as a leading cause of cancer-related death, is triggered by the
complex interplay of host genetics and environmental factors. Mounting evidence has shed …

Microbiota and colorectal cancer: from gut to bedside

M Silva, V Brunner, M Tschurtschenthaler - Frontiers in pharmacology, 2021 - frontiersin.org
Colorectal cancer (CRC) is a complex condition with heterogeneous aetiology, caused by a
combination of various environmental, genetic, and epigenetic factors. The presence of a …

Gut microbiota in colorectal cancer: mechanisms of action and clinical applications

SH Wong, J Yu - Nature reviews Gastroenterology & hepatology, 2019 - nature.com
Colorectal cancer (CRC) accounts for about 10% of all new cancer cases globally. Located
at close proximity to the colorectal epithelium, the gut microbiota comprises a large …

Role of gut microbiota in the development and treatment of colorectal cancer

C Lin, X Cai, J Zhang, W Wang, Q Sheng, H Hua… - Digestion, 1963 - karger.com
Human guts harbor abundant microbes that regulate many aspects of host physiology.
However, bacterial imbalance or dysbiosis in the gut due to the dietary or environmental …