Background Bipolar disorder affects up to one in 25 individuals and identification of early
risk indicators of negative outcomes could facilitate early detection of patients with greatest …

DaruyFilho L, Brietzke E, Lafer B, GrassiOliveira R. Childhood maltreatment and clinical
outcomes of bipolar disorder. Objective: Adverse life events, especially early trauma, play a …

Maniglio R. The impact of child sexual abuse on the course of bipolar disorder: a systematic
review. Bipolar Disord 2013: 15: 341–358.© 2013 John Wiley & Sons A/S. Published by …

Background Previous studies in bipolar disorder investigating childhood trauma and clinical
presentations of the illness have mainly focused on physical and sexual abuse. Our aim was …

BackgroundThe relationship between childhood adversity and bipolar affective disorder
remains unclear. AimsTo understand the size and significance of this effect through a …

BackgroundFew investigations have examined the impact of childhood trauma, and
domains of childhood abuse, on outcome in bipolar disorder. AimsTo evaluate the …

Objectives Physical or sexual abuse in childhood is known to have an adverse effect on the
course of bipolar disorder, but the impact of verbal abuse has not been well elucidated …

BackgroundThere has been increasing interest in the association between childhood
trauma and psychosis. Proposals for potential mechanisms involved include affective …

To estimate the prevalence and social and demographic correlates of child sexual abuse
among people with bipolar disorder, the findings of all the pertinent studies were …

Objective Childhood maltreatment has been linked to impairments in social functioning and
social cognition in adults with affective disorders. However, conclusions have been limited …