Neurotransmitter changes in Alzheimer's disease: implications to diagnostics and therapy
KJ Reinikainen, H Soininen… - Journal of neuroscience …, 1990 - Wiley Online Library
Abstract Changes in the cholinergic, serotonergic, noradrenergic, dopaminergic, GABAergic
and somatostatinergic neurons were investigated to determine their roles in Alzheimer's …
and somatostatinergic neurons were investigated to determine their roles in Alzheimer's …
Neurochemical correlates of dementia severity in Alzheimer's disease: relative importance of the cholinergic deficits
LM Bierer, V Haroutunian, S Gabriel… - Journal of …, 1995 - Wiley Online Library
Cholinergic markers, neuropeptides, and amines and their metabolites were sampled from
identical specimens across 10 neocortical regions in a large sample of Alzheimer's disease …
identical specimens across 10 neocortical regions in a large sample of Alzheimer's disease …
Neurotransmitter and receptor deficits in senile dementia of the Alzheimer type
R Quirion, JC Martel, Y Robitaille, P Etienne… - Canadian Journal of …, 1986 - cambridge.org
Multiple neurotransmitter systems are affected in senile dementia of the Alzheimer's type
(SDAT). Among them, acetylcholine has been most studied. It is now well accepted that the …
(SDAT). Among them, acetylcholine has been most studied. It is now well accepted that the …
A post-mortem study of noradrenergic, serotonergic and GABAergic neurons in Alzheimer's disease
KJ Reinikainen, L Paljärvi, M Huuskonen… - Journal of the …, 1988 - Elsevier
Involvement of noradrenergic, serotonergic and GABAergic neurons in Alzheimer's
disease/senile dementia of Alzheimer type (AD/SDAT) was studied in 20 histologically …
disease/senile dementia of Alzheimer type (AD/SDAT) was studied in 20 histologically …
Clinical studies of the cholinergic deficit in Alzheimer's disease: I. Neurochemical and neuroendocrine studies
BM Davis, RC Mohs, BS Greenwald… - Journal of the …, 1985 - Wiley Online Library
Autopsy studies indicating that cholinergic neurons are selectively lost in patients with
Alzheimer's disease (AD) and senile dementia of the Alzheimer type (SDAT) suggest that …
Alzheimer's disease (AD) and senile dementia of the Alzheimer type (SDAT) suggest that …
Neurotransmitter receptor alterations in Alzheimer disease: a review
PJ Whitehouse - Alzheimer Disease & Associated Disorders, 1987 - journals.lww.com
In Alzheimer disease (AD), dysfunction in several neuronal systems is associated with
alterations in neurotransmitter receptors. Although receptors are important components of …
alterations in neurotransmitter receptors. Although receptors are important components of …
Decreased somatostatin-like immunoreactivity in cerebral cortex and cerebrospinal fluid in Alzheimer's disease
KJ Reinikainen, PJ Riekkinen, J Jolkkonen, VM Kosma… - Brain research, 1987 - Elsevier
To investigate changes in the somatostatinergic neurons of patients with Alzheimer's
disease (AD), we determined the somatostatin-like immunoreactivity (SLI) in post-mortem …
disease (AD), we determined the somatostatin-like immunoreactivity (SLI) in post-mortem …
The cholinergic system in Alzheimer disease
E Giacobini - Progress in brain research, 1990 - Elsevier
Publisher Summary This chapter describes the cholinergic system in Alzheimer disease
(AD). Choline acetyltransferase (ChAT), the synthetic enzyme for acetylcholine (ACh), is …
(AD). Choline acetyltransferase (ChAT), the synthetic enzyme for acetylcholine (ACh), is …
Biochemical assessment of serotonergic and cholinergic dysfunction and cerebral atrophy in Alzheimer's disease
DM Bowen, SJ Allen, JS Benton… - Journal of …, 1983 - Wiley Online Library
Markers of serotonin synapses in entire temporal lobe and frontal and temporal neocortex
were examined for changes in Alzheimer's disease by use of both neurosurgical and …
were examined for changes in Alzheimer's disease by use of both neurosurgical and …
Differential correlation between neurochemical deficits, neuropathology, and cognitive status in Alzheimer's disease
P Dournaud, P Delaere, JJ Hauw, J Epelbaum - Neurobiology of aging, 1995 - Elsevier
The relationships between neurofibrillary tangles (NFT), senile plaques (SP), and the deficits
in somatostatin (SRIH) and choline acetyltransferase (ChAT) levels were determined in …
in somatostatin (SRIH) and choline acetyltransferase (ChAT) levels were determined in …
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