Medicinal chemistry and pharmacology of genus Tripterygium (Celastraceae)

AM Brinker, J Ma, PE Lipsky, I Raskin - Phytochemistry, 2007 - Elsevier
Plants in the genus Tripterygium, such as Tripterygium wilfordii Hook. f., have a long history
of use in traditional Chinese medicine. In recent years there has been considerable interest …

Immunosuppressive and Anti-Inflammatory Mechanisms of Triptolide, the Principal Active Diterpenoid from the Chinese Medicinal Herb Tripterygium wilfordii Hook. f.

D Qiu, PN Kao - Drugs in R & D, 2003 - Springer
Extracts of Tripterygium wilfordii hook. f.(leigong teng, Thundergod vine) are effective in
traditional Chinese medicine for treatment of immune inflammatory diseases including …

Triptolide, a novel immunosuppressive and anti-inflammatory agent purified from a Chinese herb Tripterygium wilfordii Hook F

BJ Chen - Leukemia & lymphoma, 2001 - Taylor & Francis
Triptolide is a diterpenoid triepoxide purified from a Chines herb Tripterygium Wilfordii Hook
F (TWHF). TWHF has been used in traditional Chinese medicine for more than two thousand …

Tripterygium wilfordii bioactive compounds as anticancer and anti-inflammatory agents.

KF Wong, Y Yuan, JM Luk - Clinical & Experimental …, 2012 - search.ebscohost.com
Bioactive compounds from medicinal plants with anticancer and anti-inflammatory effects
have become key resources in drug discovery fields for the treatment of various …

The genus Tripterygium: A phytochemistry and pharmacological review

H Lv, L Jiang, M Zhu, Y Li, M Luo, P Jiang, S Tong… - Fitoterapia, 2019 - Elsevier
The genus Tripterygium belongs to the family Celastraceae, and contains three species, ie
Tripterygium wilfordii Hook. F, Tripterygium hypoglaucum (Levl.) Hutch. and Tripterygium …

Anti-inflammatory and immunosuppressive compounds from Tripterygium wilfordii

J Ma, M Dey, H Yang, A Poulev, R Pouleva, R Dorn… - Phytochemistry, 2007 - Elsevier
The extract of Tripterygium wilfordii Hook F.(TwHF), which showed anti-inflammatory and
immunosuppressive activities in human clinical trials for rheumatoid arthritis, was subjected …

Tripterygium hypoglaucum (Lévl.) Hutch and Its Main Bioactive Components: Recent Advances in Pharmacological Activity, Pharmacokinetics and Potential Toxicity

J Zhao, F Zhang, X Xiao, Z Wu, Q Hu, Y Jiang… - Frontiers in …, 2021 - frontiersin.org
Tripterygium hypoglaucum (Lévl.) Hutch (THH) is believed to play an important role in health
care and disease treatment according to traditional Chinese medicine. Moreover, it is also …

[HTML][HTML] Immunosuppressive, anti-inflammatory and anti-cancer properties of triptolide: A mini review

S Ziaei, R Halaby - Avicenna journal of phytomedicine, 2016 - ncbi.nlm.nih.gov
Objective: Triptolide, the active component of Tripterygium wilfordii Hook F has been used to
treat autoimmune and inflammatory conditions for over two hundred years in traditional …

Isolation, purification, and characterization of immunosuppressive compounds from tripterygium: triptolide and tripdiolide

WZ Gu, R Chen, S Brandwein, J McAlpine… - International journal of …, 1995 - Elsevier
Crude extracts derived from the root of Tripterygium wilfordii Hook f (TWHf) have previously
been demonstrated to have immunosuppressive properties and have been used as anti …

[HTML][HTML] A comprehensive review on celastrol, triptolide and triptonide: Insights on their pharmacological activity, toxicity, combination therapy, new dosage form and …

J Song, GN He, L Dai - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Celastrol, triptolide and triptonide are the most significant active ingredients of Tripterygium
wilfordii Hook F (TWHF). In 2007, the 'Cell'journal ranked celastrol, triptolide, artemisinin …