Clinical biology of the pituitary adenoma
S Melmed, UB Kaiser, MB Lopes, J Bertherat… - Endocrine …, 2022 - academic.oup.com
All endocrine glands are susceptible to neoplastic growth, yet the health consequences of
these neoplasms differ between endocrine tissues. Pituitary neoplasms are highly prevalent …
these neoplasms differ between endocrine tissues. Pituitary neoplasms are highly prevalent …
Pituitary tumor pathogenesis
I Shimon, S Melmed - The Journal of Clinical Endocrinology & …, 1997 - academic.oup.com
Pituitary tumors are mostly benign monoclonal adenomas arising from adenohypophyseal
cells in the anterior pituitary. These tumors usually autonomously express and secrete …
cells in the anterior pituitary. These tumors usually autonomously express and secrete …
Pathogenesis of pituitary tumors
S Melmed - Nature Reviews Endocrinology, 2011 - nature.com
Pituitary adenomas may hypersecrete hormones (including prolactin, growth hormone and
adrenocorticotropic hormone, and rarely follicle-stimulating hormone, luteinizing hormone or …
adrenocorticotropic hormone, and rarely follicle-stimulating hormone, luteinizing hormone or …
Mechanisms of disease: the pathogenesis of pituitary tumors
Pituitary tumors exhibit a spectrum of biology, with variable growth and hormonal behaviors.
They therefore provide an opportunity to examine pathogenetic mechanisms that underlie …
They therefore provide an opportunity to examine pathogenetic mechanisms that underlie …
The pathogenesis of pituitary tumors
Recently there has been significant progress in our understanding of pituitary development,
physiology, and pathology. New information has helped to clarify the classification of …
physiology, and pathology. New information has helped to clarify the classification of …
Epidemiology and etiopathogenesis of pituitary adenomas
ED Aflorei, M Korbonits - Journal of neuro-oncology, 2014 - Springer
Pituitary adenomas are usually benign monoclonal tumours presenting either due to
hypersecretion of pituitary hormones, and/or due to local space occupying effects and …
hypersecretion of pituitary hormones, and/or due to local space occupying effects and …
Novel insights into pituitary tumorigenesis: genetic and epigenetic mechanisms
V Srirangam Nadhamuni, M Korbonits - Endocrine reviews, 2020 - academic.oup.com
Substantial advances have been made recently in the pathobiology of pituitary tumors.
Similar to many other endocrine tumors, over the last few years we have recognized the role …
Similar to many other endocrine tumors, over the last few years we have recognized the role …
Molecular defects in the pathogenesis of pituitary tumours
A Levy, S Lightman - Frontiers in Neuroendocrinology, 2003 - Elsevier
The majority of pituitary adenomas are trophically stable and change relatively little in size
over many years. A comparatively small proportion behave more aggressively and come to …
over many years. A comparatively small proportion behave more aggressively and come to …
Landscape of genomic alterations in pituitary adenomas
Purpose: Pituitary adenomas are the second most common primary brain tumor, yet their
genetic profiles are incompletely understood. Experimental Design: We performed whole …
genetic profiles are incompletely understood. Experimental Design: We performed whole …
Clinicopathological correlations in pituitary adenomas
Pituitary adenomas are common neuroendocrine neoplasms arising from adenohypophysial
cells. Recent progress in our understanding of pituitary tumorigenesis as well as pathways …
cells. Recent progress in our understanding of pituitary tumorigenesis as well as pathways …