Synthesis and investigation of the analgesic potential of enantiomerically pure schiff bases: a mechanistic approach

HH Afridi, M Shoaib, FA Al-Joufi, SWA Shah, H Hussain… - Molecules, 2022 - mdpi.com
Schiff bases are a class of organic compounds with azomethine moiety, exhibiting a wide
range of biological potentials. In this research, six chiral Schiff bases, three 'S'series (H1 …

[PDF][PDF] A systemic review of schiff bases as an analgesic, anti-inflammatory

K Rana, A Pandurangan, N Singh… - Int. J. Curr. Pharm. Res, 2012 - academia.edu
Schiff bases are aldehyde-or ketone-like compounds in which the carbonyl group is
replaced by an imine or azomethine group. They are widely used for industrial purposes and …

A class of novel Schiff's bases: Synthesis, therapeutic action for chronic pain, anti-inflammation and 3D QSAR analysis

Y Zhou, M Zhao, Y Wu, C Li, J Wu, M Zheng… - Bioorganic & medicinal …, 2010 - Elsevier
To discover analgesics for treating chronic pain 17 novel Schiff's bases, N, N′-(Z-allylidene-
1, 3-diyl) bisamino acid methyl esters were prepared from 1, 1, 3, 3,-tetramethoxypropane …

Synthesis, analgesic, anti-inflammatory and anti-ulcerogenic activities of certain novel Schiff's bases as fenamate isosteres

AM Alafeefy, MA Bakht, MA Ganaie, MN Ansarie… - Bioorganic & medicinal …, 2015 - Elsevier
A series of certain novel Schiff bases as fenamate isosteres (VI: a–k) were synthesized to
locate analgesic, anti-inflammatory agent with minimal ulcerogenic potential. The structures …

Synthesis of biologically active novel bis Schiff bases, bis hydrazone and bis guanidine derivatives

SM Sondhi, M Dinodia, S Jain, A Kumar - 2009 - nopr.niscpr.res.in
A number of bis Schiff′ s bases 3a-d have been synthesized by condensation of 2, 4, 8, 10
tetraoxaspiro [5, 5] undecane 3, 9-dipropanamine 1 with furfural, indole-3-aldehyde, 2 …

[PDF][PDF] Schiff bases derived from 1-aminoanthraquinone: a new class of analgesic compounds

G Fareed, GH Rizwani, M Ahmed, MA Versiani… - Pakistan Journal of …, 2017 - v3.pjsir.org
Schiff Bases Derived from 1-Aminoanthraquinone: A New Class of Analgesic Compounds Page
1 Schiff Bases Derived from 1-Aminoanthraquinone: A New Class of Analgesic Compounds …

[PDF][PDF] Schiff bases as important class of pharmacological agents

ADA Sykula - Journal of Pharmacy and Pharmacology, 2018 - academia.edu
Therapeutics are compounds, which do not always exhibit healing powers. They sometimes
prevent or control roles. Many compounds, well known or less are treated as the therapeutic …

Identification of the first marine-derived opioid receptor “balanced” agonist with a signaling profile that resembles the endorphins

TA Johnson, L Milan-Lobo, T Che… - ACS chemical …, 2017 - ACS Publications
Opioid therapeutics are excellent analgesics, whose utility is compromised by dependence.
Morphine (1) and its clinically relevant derivatives such as OxyContin (2), Vicodin (3), and …

[HTML][HTML] Synthesis and biological evaluation of schiff bases of 4-aminophenazone as an anti-inflammatory, analgesic and antipyretic agent

S Murtaza, MS Akhtar, F Kanwal, A Abbas… - Journal of Saudi …, 2017 - Elsevier
A series of schiff base derivatives of 4-aminophenazone (4APZ-1, 5-dimethyl-2-phenyl-1, 2-
dihydro-3H-pyrazol-3-one) with different aldehydes were synthesized. The synthetic …

A pair of Schiff base enantiomers studied by absorption, fluorescence, electronic and vibrational circular dichroism spectroscopies and density functional theory …

HH Tang, L Zhang, LL Zeng, XM Fang, LR Lin… - RSC Advances, 2015 - pubs.rsc.org
2-(((1R, 2S)-2-Hydroxy-1, 2-diphenylethylimino) methyl) phenol and 2-(((1S, 2R)-2-hydroxy-
1, 2-diphenylethylimino) methyl) phenol have been synthesized as a pair of enantiomeric …