A multi-domain intervention protocol for the potential reversal of cognitive frailty:“WE-RISE” randomized controlled trial

RR Murukesu, DKA Singh, S Shahar… - Frontiers in public …, 2020 - frontiersin.org
Following the rapid increase of the aging population, health promotion and prevention of
physical disability and dementia in older persons are essential for healthy aging. For …

Multidomain intervention for reversal of cognitive frailty, towards a personalized approach (AGELESS Trial): study design

P Ponvel, S Shahar, DKA Singh… - Journal of …, 2021 - content.iospress.com
Background: Cognitive frailty (CF) is identified as one of the main precursors of dementia.
Multidomain intervention has been found to delay or prevent the onset of CF. Objective: The …

SINgapore GERiatric intervention study to reduce physical frailty and cognitive decline (SINGER)–pilot: A feasibility study

KA Chew, X Xu, P Siongco, S Villaraza… - … Research & Clinical …, 2021 - Wiley Online Library
Introduction The SINGER pilot randomized controlled trial aims to examine the feasibility
and acceptability of the Finnish Geriatric Intervention Study (FINGER) multidomain lifestyle …

The Singapore geriatric intervention study to reduce cognitive decline and physical frailty (SINGER): study design and protocol

X Xu, KA Chew, ZX Wong, AKS Phua… - The Journal of …, 2022 - Springer
Abstract Background The SINgapore GERiatric intervention study to reduce cognitive
decline and physical frailty (SINGER) randomised controlled trial (RCT) uses a multidomain …

Effectiveness of interventions in older adults with cognitive frailty: a systematic review and meta-analysis of randomised controlled trials

L Zheng, C Wang, Y Qiu, X Li, X Zhang… - Age and …, 2022 - academic.oup.com
Background interventions targeting older adults with cognitive frailty have grown rapidly in
recent years with inconsistent findings. However, there is no meta-analysis that has …

Exercise interventions for older people with cognitive frailty—a scoping review

X Li, Y Zhang, Y Tian, Q Cheng, Y Gao, M Gao - BMC geriatrics, 2022 - Springer
Background As the global population ages, the issue of frailty in older people is gaining
international attention. As one of the major subtypes of frailty, cognitive frailty is a …

The effects of interventions to enhance cognitive and physical functions in older people with cognitive frailty: A systematic review and meta-analysis

ACY Tam, AWY Chan, DSK Cheung, LYW Ho… - European Review of …, 2022 - Springer
Introduction Cognitive frailty is the co-existence of mild cognitive impairment and physical
frailty that increases the risk of adverse health outcomes. The existing systematic reviews on …

Efficacy of multidomain interventions to improve physical frailty, depression and cognition: data from clusterrandomized controlled trials

LK Chen, AC Hwang, WJ Lee, LN Peng… - Journal of cachexia …, 2020 - Wiley Online Library
Background Frailty is the preeminent exigency of aging. Although frailtyrelated
impairments are preventable, and multidomain interventions appear more effective than …

Management of cognitive frailty: A network metaanalysis of randomized controlled trials

Y Zhang, JJ Zhou, XM Zhang, JT Liu… - … Journal of Geriatric …, 2023 - Wiley Online Library
Objectives We aimed to compare the effectiveness of interventions in cognitive function and
frailty status and rank these interventions. Methods Data SourcesWe searched PubMed …

Update on interventions to prevent or reduce frailty in community-dwelling older adults: A scoping review and community translation

X Liu, DHM Ng, JWT Seah, YL Munro… - Current Geriatrics Reports, 2019 - Springer
Abstract Purpose of Review With increasing interest in frailty prevention and management
globally, this scoping review provides an update to the current knowledge on interventions …