… that loss of myelin integrity could be … of myelin dysfunction and demyelinating injuries as
potent drivers of amyloid deposition in mouse models of AD. Mechanistically, myelin dysfunction …

… disease, eg Braak stage I/II within the temporal cortex, which also confirms that myelin
dysfunction … Alzheimer disease: linking beta-amyloid to myelin. JAMA Neurol 2017; 74: 17-9. 57. …

… myelin generation and loss in the APP/PS1 mouse model of AD. Unexpectedly, we observed
a dramatic increase in the rate of new myelin … overall levels of myelination are decreased in …

… process of myelination in reverse. The ensuing homeostatic responses to myelin breakdown
… distribution of AD lesions that eventually cause neuronal dysfunction and degeneration. …

… pathways of myelin injury in neurodegenerative diseases, especially the Alzheimer's disease
to … And the dysfunction of myelin may be a phenomenon of preclinical AD. These results …

… In this work, we describe the possible role of early myelin alterations in the genesis of … of
the disease may arise from structural and metabolic disorders in the processes of myelination/…

… of myelin is associated with Alzheimer's disease (AD) since the vulnerability of oligodendrocytes
under Alzheimer's pathology easily induces the myelin … and myelin dysfunction in AD …

… of myelin in the forebrain provides protection against plaque deposition. Mechanistically,
we find that myelin dysfunction … Surprisingly, AD mice with dysfunctional myelin lack plaque-…

… of myelin, to repair myelin … myelin production and remyelination processes, changes in the
number of oligodendrocytes or their precursor cells and/or their dysfunction can affect myelin …

… in cognitive dysfunction, such as Alzheimer’s disease, … in neurodegenerative diseases and
cerebral vascular diseases [… of Parkinson disease (PD), 6 cases of Alzheimer disease (AD), …