… n = 1,016), we tested whether astrocyte reactivity modulates the … tau only in individuals
positive for astrocyte reactivity (Ast + ). … Our findings suggest astrocyte reactivity as an important …

… availability of amyloid-associated proteins, especially apolipoprotein E (apoE). Astrocytes
from … Reactive astrocytes and Aβ containing astrocytes are common findings in the AD brain. A …

… Elevated levels of IL-1 prior to astrogliosis were detected, which suggest the involvement
of IL-1 in the regulation of astrocyte reactivity associated with increased GFAP and S100B …

… analyses demonstrated that reactive astrocytes can acquire multiple … of astrocyte reactivity
[8] raise the possibility that astrocytes … We also investigated whether these reactive astrocyte …

… glial (astrocytes and microglia) cultures that had been exposed to Aβ. Microglia exposed to
Aβ responded with reactive … We found that the reactivity in response to Aβ was mild, but it was …

… reactive astrocytosis to disease progression are not known. We examined the possibility that
the amyloid-β (Aβ) peptide, a major constituent of the amyloid … rat cortical astrocyte cultures …

… This was demonstrated in histological studies that showed highly increased astrocyte reactivity
in AD-vulnerable areas, Aβ deposits, and oxidative damage of AD-sensitive hippocampal …

… Here, we propose a model including reactive astrocytes. In … the early stage of astrocyte
reactivity. With further pathological … , late- and end-stage reactive astrocytes can be measured with …

… what extent astrocyte reactivity, reactive astrogliosis, and corresponding changes in the
astrocyte network … Indeed, the available evidence suggests that reactive astrogliosis in different …

… cohorts, we tested whether astrocyte reactivity modulates the … levels only in individuals positive
for astrocyte reactivity (Ast+). … Our findings suggest that increased astrocyte reactivity is an …