[HTML][HTML] Biological impact and therapeutic perspective of targeting PI3K/Akt signaling in hepatocellular carcinoma: Promises and Challenges
MDA Paskeh, F Ghadyani, M Hashemi… - Pharmacological …, 2023 - Elsevier
… Among these, PI3K/Akt signaling contributes to proliferation, invasion, and inhibition of …
on the role of PI3K/Akt signaling in HCC progression. Activation of PI3K/Akt signaling promotes …
on the role of PI3K/Akt signaling in HCC progression. Activation of PI3K/Akt signaling promotes …
PIM kinase (and Akt) biology and signaling in tumors
NA Warfel, AS Kraft - Pharmacology & therapeutics, 2015 - Elsevier
… The PI3K/Akt signaling pathway is activated in many human tumors, and it is well … biological
impact of their interaction with the Akt signaling pathway on the efficacy of cancer therapy. …
impact of their interaction with the Akt signaling pathway on the efficacy of cancer therapy. …
Targeting PI3K/AKT/mTOR pathway in breast cancer: from biology to clinical challenges
K Cerma, F Piacentini, L Moscetti, M Barbolini… - Biomedicines, 2023 - mdpi.com
… PI3K-mutated HR+ metastatic (M)BC [10]. This review aims to point out the role of PI3K/AKT/mTOR
pathway mutations in the different BC subtypes, with a focus on their clinical impact …
pathway mutations in the different BC subtypes, with a focus on their clinical impact …
PI3K/AKT/mTOR pathway in multiple myeloma: from basic biology to clinical promise
V Ramakrishnan, S Kumar - Leukemia & lymphoma, 2018 - Taylor & Francis
… Here, we review the central role played by the PI3K/AKT/mTOR pathway in multiple myeloma
(MM) growth and survival, promising preclinical results from studies examining inhibitors of …
(MM) growth and survival, promising preclinical results from studies examining inhibitors of …
Interplay between PI3K/AKT pathway and heart disorders
S Ghafouri-Fard, A Khanbabapour Sasi… - Molecular biology …, 2022 - Springer
… Notably, a PI3K/mTOR inhibitor could reverse the impact of BMI1 on cardiac fibroblasts. …
of the PTEN/PI3K/AKT/mTOR pathway [17]. Table 1 shows the role of PI3K/AKT pathway in I/R …
of the PTEN/PI3K/AKT/mTOR pathway [17]. Table 1 shows the role of PI3K/AKT pathway in I/R …
[HTML][HTML] Biology and therapeutic potential of PI3K signaling in ER+/HER2-negative breast cancer
… To more comprehensively understand the impact of PI3K activation on the ER pathway, we
… As described in this review, activation of PI3K/AKT signaling is involved in at least three …
… As described in this review, activation of PI3K/AKT signaling is involved in at least three …
Ischemic time impacts biological integrity of phospho-proteins in PI3K/Akt, Erk/MAPK, and p38 MAPK signaling networks
TR Holzer, AD Fulford, AM Arkins, JM Grondin… - Anticancer …, 2011 - ar.iiarjournals.org
… impact on the ability to elucidate signaling pathways in tissue. Immunohistochemical analysis
of phosphorylated proteins involved in PI3K/Akt… to preserve the biological integrity of signal …
of phosphorylated proteins involved in PI3K/Akt… to preserve the biological integrity of signal …
The emerging role of PI3K/AKT-mediated epigenetic regulation in cancer
JM Spangle, TM Roberts, JJ Zhao - … et Biophysica Acta (BBA)-Reviews on …, 2017 - Elsevier
… PI3K/AKT pathway regulates the epigenome to promote oncogenesis, and highlight how
connections between PI3K/AKT and the epigenome may impact … are biologically active against …
connections between PI3K/AKT and the epigenome may impact … are biologically active against …
The PTEN/PI3K/AKT signalling pathway in cancer, therapeutic implications
A Carnero, C Blanco-Aparicio, O Renner… - Current cancer drug …, 2008 - ingentaconnect.com
… /PI3K/AKT constitutes an important pathway regulating the signaling of multiple biological …
the Rad51 promoter suggesting a more direct impact of PTEN on transcriptional regulation […
the Rad51 promoter suggesting a more direct impact of PTEN on transcriptional regulation […
PLC and PI3K/Akt/mTOR signalling in disease and cancer
MY Follo, L Manzoli, A Poli, JA McCubrey… - Advances in biological …, 2015 - Elsevier
… For instance, PI3K/Akt/mTOR is associated with normal proliferation and differentiation, and
its … Here, we review the role of PLC and PI3K/Akt/mTOR signal transduction pathways in …
its … Here, we review the role of PLC and PI3K/Akt/mTOR signal transduction pathways in …
相关搜索
- pi3k akt mtor pathway
- pi3k akt mtor inhibitors
- role of pi3k akt
- biological integrity pi3k akt
- egfr pi3k akt mtor
- pi3k akt signal transduction
- pten pi3k akt
- therapeutic perspective biological impact
- pi3k akt mtor signaling
- pi3k akt mtor hepatocellular carcinoma metabolism
- pi3k akt mtor disease and cancer
- breast cancer cohorts pi3k akt
- promises and challenges biological impact
- implications for targeted therapeutics pi3k akt
- mutational landscape pi3k akt
- tumor cell pi3k akt