Nucleus basalis of Meynert degeneration precedes and predicts cognitive impairment in Parkinson's disease

J Schulz, G Pagano, JA Fernández Bonfante, H Wilson… - Brain, 2018 - academic.oup.com
cognitive impairment in Parkinson’s disease. Our findings provide evidence that degeneration
of the nucleus basalis of Meynert precedes and predicts the onset of cognitive impairment, …

[HTML][HTML] Structural Degeneration of the Nucleus basalis of Meynert in Mild Cognitive Impairment and Alzheimer's Disease–Evidence from an MRI-based Meta-Analysis

M Mieling, H Meier, N Bunzeck - Neuroscience & Biobehavioral Reviews, 2023 - Elsevier
… degenerations of the cholinergic Nucleus basalis of Meynert (NbM). Evidence from imaging
… for such an effect in patients with mild cognitive impairment (MCI), which typically precedes …

Nucleus basalis of Meynert degeneration predicts cognitive impairment in Parkinson's disease

H Wilson, ER de Natale, M Politis - Handbook of Clinical Neurology, 2021 - Elsevier
… of Meynert (… Dysfunction of the cholinergic system and degeneration of the NBM have
been implicated in the pathophysiology of cognitive impairment in neurodegenerative disorders

[HTML][HTML] Nucleus basalis of Meynert degeneration predicts cognitive decline in corticobasal syndrome

D Urso, S Nigro, B Tafuri, R De Blasi, JB Pereira… - Biological …, 2024 - Elsevier
… Next, we assessed whether gray matter degeneration of the NbM evaluated at baseline
could predict cognitive impairment during a 12-month follow-up period in patients with CBS. All …

[HTML][HTML] In vivo nucleus basalis of Meynert degeneration in mild cognitive impairment with Lewy bodies

J Schumacher, JP Taylor, CA Hamilton, M Firbank… - NeuroImage: Clinical, 2021 - Elsevier
… This study provides in vivo evidence that early cholinergic degeneration in DLB occurs at
the MCI stage and is related to the severity of cognitive impairment. Furthermore, the results …

[HTML][HTML] Degeneration of cholinergic white matter pathways and nucleus basalis of Meynert in individuals with objective subtle cognitive impairment

T Qiu, H Hong, Q Zeng, X Luo, X Wang, X Xu, F Xie… - Neurobiology of …, 2023 - Elsevier
… We evaluated alterations in the nucleus basalis of Meynert (NBM) volume and integrity of
cholinergic white matter pathways in objective subtle cognitive impairment (Obj-SCI) individuals…

[HTML][HTML] Meynert nucleus-related cortical thinning in Parkinson's disease with mild cognitive impairment

S Rong, Y Li, B Li, K Nie, P Zhang, T Cai… - … Imaging in Medicine …, 2021 - ncbi.nlm.nih.gov
… ) and neocortex (11,12) were found to be degenerative in PD with dementia (PDD). However,
degeneration is one of the specific pathological changes in PD with cognitive impairment. …

Nucleus basalis of Meynert degeneration predicts cognitive impairment in Parkinson's disease

DF Swaab, F Kreier, PJ Lucassen… - The Human …, 2021 - books.google.com
cognitive impairment in PD. Given the link between cholinergic dysfunction and the pathogenesis
of cognitive decline … the role of the NBM underlying cognitive performance. Recently, …

Altered functional connectivity of the basal nucleus of Meynert in subjective cognitive impairment, early mild cognitive impairment, and late mild cognitive impairment

W Xu, J Rao, Y Song, S Chen, C Xue, G Hu… - Frontiers in Aging …, 2021 - frontiersin.org
… standard neurocognitive assessments to evaluate their cognitive function, including general
cognitive functions, episodic memory, executive function, information processing speed, and …

The cholinergic system in aging and neuronal degeneration

R Schliebs, T Arendt - Behavioural brain research, 2011 - Elsevier
… , and nucleus basalis of Meynert provides the mayor … cognitive impairments are due to loss
of cholinergic function. ▶ In inherited and late AD basal forebrain cholinergic cells degenerate