Strategies for controlled delivery of growth factors and cells for bone regeneration

TN Vo, FK Kasper, AG Mikos - Advanced drug delivery reviews, 2012 - Elsevier
delivery systems for augmenting bone regeneration. The general requirements of protein,
cell … and processing affects growth factor and cell delivery and regenerative efficacy in both in …

Controlled growth factor delivery for tissue engineering

P Tayalia, DJ Mooney - Advanced materials, 2009 - Wiley Online Library
… for growth factor delivery vehicles with respect to the growth factor itself and the microenvironment
for delivery. … delivery, and strategies using polymers as delivery vehicles in particular. …

Toward delivery of multiple growth factors in tissue engineering

FM Chen, M Zhang, ZF Wu - Biomaterials, 2010 - Elsevier
… (A), act on adjacent cells (B), or act on long-distance cells (C) (illustration is not to scale). …
cell types can produce the same growth factor, and the same growth factor can act on many cell

Localized delivery of growth factors for bone repair

V Luginbuehl, L Meinel, HP Merkle, B Gander - European journal of …, 2004 - Elsevier
growth factor therapies so far. This review summarizes various approaches for … growth factor
delivery as focused on bone repair. Similar considerations may apply to other growth factors

Growth factor delivery for tissue engineering

JE Babensee, LV McIntire, AG Mikos - Pharmaceutical research, 2000 - Springer
… Specific growth factors, released from a delivery device or from co-transplanted cells, would
aid in the induction of host paraenchymal cell … of co-delivered cells for more efficient tissue …

Biopolymeric delivery matrices for angiogenic growth factors

AH Zisch, MP Lutolf, JA Hubbell - Cardiovascular pathology, 2003 - Elsevier
… interaction with the growth factor molecules or cells delivered by the matrix nor sites for
specific signaling interactions with cells of the target tissue. Delivery of growth factor proteins from …

In vitro effects of combined and sequential delivery of two bone growth factors

AT Raiche, DA Puleo - Biomaterials, 2004 - Elsevier
… , cells were also treated with soluble growth factors directly … 2 (C3H) cells responded to soluble
growth factor treatments with … delivery of multiple growth factors can significantly affect cell

Polymeric growth factor delivery strategies for tissue engineering

RR Chen, DJ Mooney - Pharmaceutical research, 2003 - Springer
… from either cells resident in the surrounding tissue or cells … of polymeric delivery systems
for growth factor delivery in … Growth factors direct the phenotype of both differentiated and …

Polymeric system for dual growth factor delivery

TP Richardson, MC Peters, AB Ennett… - Nature …, 2001 - nature.com
… -specific delivery of two or more growth factors, with controlled dose and rate of delivery.
The … We now demonstrate that dual delivery of vascular endothelial growth factor (VEGF)-165 …

Nanoparticulate systems for growth factor delivery

S Zhang, H Uludağ - Pharmaceutical research, 2009 - Springer
… for delivery of various drugs (18). This review is an update on NP delivery systems with
special focus on growth factor delivery. An overview of design criteria for growth factor delivery