Docosahexaenoic acid affects cell signaling by altering lipid rafts
W Stillwell, SR Shaikh, M Zerouga… - Reproduction …, 2005 - rnd.edpsciences.org
… Abstract – With 22 carbons and 6 double bonds docosahexaenoic acid (DHA) is the longest
and most unsaturated fatty acid commonly found in membranes. It represents the extreme …
and most unsaturated fatty acid commonly found in membranes. It represents the extreme …
Docosahexaenoic acid regulates the formation of lipid rafts: A unified view from experiment and simulation
SR Wassall, X Leng, SW Canner… - … et Biophysica Acta (BBA …, 2018 - Elsevier
… acyl chains of PC lipids tune the size of lipid rafts, which has potential implications for
signaling networks that rely on the compartmentalization of proteins within and outside of rafts. …
signaling networks that rely on the compartmentalization of proteins within and outside of rafts. …
Docosahexaenoic acid domains: the ultimate non-raft membrane domain
SR Wassall, W Stillwell - Chemistry and physics of lipids, 2008 - Elsevier
… These domains are compositionally and organizationally the antithesis of lipid rafts, the …
-rich domains into the plasma membrane where they coexist with lipid rafts is the origin, in part, …
-rich domains into the plasma membrane where they coexist with lipid rafts is the origin, in part, …
Docosahexaenoic acid changes lipid composition and interleukin-2 receptor signaling in membrane rafts
Q Li, M Wang, L Tan, C Wang, J Ma, N Li, Y Li… - Journal of lipid …, 2005 - ASBMB
… lipid composition in lipid rafts and membrane subdomain distribution of interleukin-2 (IL-2)
receptor signaling molecules. We found that DHA altered lipid components of rafts … lipid rafts. …
receptor signaling molecules. We found that DHA altered lipid components of rafts … lipid rafts. …
[HTML][HTML] Docosahexaenoic acid modifies the clustering and size of lipid rafts and the lateral organization and surface expression of MHC class I of EL4 cells
SR Shaikh, BD Rockett, K Carraway - The Journal of nutrition, 2009 - Elsevier
… -lipid raft biophysical liposome model at a cellular level. We measured the effects of oleic
acid (OA), the (n-3) PUFA eicosapentaenoic acid (EPA), and DHA treatment on EL4 cell raft …
acid (OA), the (n-3) PUFA eicosapentaenoic acid (EPA), and DHA treatment on EL4 cell raft …
Dietary docosahexaenoic acid suppresses T cell protein kinase Cθ lipid raft recruitment and IL-2 production
YY Fan, LH Ly, R Barhoumi, DN McMurray… - The Journal of …, 2004 - journals.aai.org
… In addition, our results demonstrate that lipid rafts exhibit a lipid composition that is distinct
from that seen in isolated bulk membrane fractions (Tables I and II). This is likely to contribute …
from that seen in isolated bulk membrane fractions (Tables I and II). This is likely to contribute …
Docosahexaenoic acid alters epidermal growth factor receptor-related signaling by disrupting its lipid raft association
KR Rogers, KD Kikawa, M Mouradian… - …, 2010 - academic.oup.com
… lipid rafts through modifications by fatty acids allowing them to tether ( 32 ), and interestingly,
DHA has also been shown to effect Ras localization to the plasma membrane … in lipid rafts, …
DHA has also been shown to effect Ras localization to the plasma membrane … in lipid rafts, …
[HTML][HTML] Inhibition of cytokine signaling in human retinal endothelial cells through modification of caveolae/lipid rafts by docosahexaenoic acid
… The lipid composition of caveolae is similar to that of lipid rafts, … lipid rafts and the initiating
factors in lipid raft assembly, 16 18 19 20 21 22 it is well accepted that caveolae and lipid rafts …
factors in lipid raft assembly, 16 18 19 20 21 22 it is well accepted that caveolae and lipid rafts …
Down-regulation of lipid raft-associated onco-proteins via cholesterol-dependent lipid raft internalization in docosahexaenoic acid-induced apoptosis
EJ Lee, UJ Yun, KH Koo, JY Sung, J Shim… - … Cell Biology of Lipids, 2014 - Elsevier
… alters the association of proteins with lipid rafts, we performed lipid raft purification. Caveolin-1
is a maker for lipid rafts, and its association with lipid raft fractions decreased in the DHA …
is a maker for lipid rafts, and its association with lipid raft fractions decreased in the DHA …
The mechanism of docosahexaenoic acid-induced phospholipase D activation in human lymphocytes involves exclusion of the enzyme from lipid rafts
O Diaz, A Berquand, M Dubois, S Di Agostino… - Journal of Biological …, 2002 - ASBMB
… the possible association of PLD enzymes with lipid rafts and to determine the mechanisms
… location of PLD isoforms inside or outside lipid rafts might be altered under the influence of …
… location of PLD isoforms inside or outside lipid rafts might be altered under the influence of …
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