… of hepatocellular carcinoma (HCC) remains challenging as reflected by low survival rates.
The PI3K/Akt/… Importantly, deregulation of the PI3K/Akt/mTOR pathway leading to activation is …

… hepatocellular carcinoma (HCC) development, the clinical management of the disease remains
a major challenge. Deregulation of the PI3K/Akt… various PI3K inhibitors, Akt inhibitors and …

… PI3K/AKT/mTOR signaling and its metabolic role in HCC is still limited. In this review, we
highlight the role of the PI3K/AKT/… trials targeting the PI3K/AKT/mTOR pathway for HCC therapy. …

… Hepatocellular carcinoma (HCC) is a primary liver cancer with high incidence rate, … the role
of PI3K/Akt signaling in HCC progression. Activation of PI3K/Akt signaling promotes glucose …

… The overexpression of PI3K and AKT or gene mutation in PTEN tumor suppressor leads
to overactivation of the PI3K pathway. In this review, we summarize the role of PI3K/AKT/mTOR …

… Our data showed that radiation could activate PI3K/Akt, MAPK/ERK, JNK and p38, but the
inhibitor of PI3K/Akt was the only one to regulate MMP-9. Ruhul Amin et al. (2003) reported …

… the mechanism by which NCAPG promotes proliferation in hepatocellular carcinoma (HCC). …
regulating the PI3K/AKT pathway. Western blotting showed that the levels of p-PI3K, p-AKT (…

… In this study, we found that treatment of hepatocellular carcinoma cells with apigenin
decreased the levels of phosphorylated Akt and mTOR. mTOR is a serine/threonine kinase that …

… The genomic landscape of hepatocellular carcinoma (HCC) … led to putative activation of the
PI3K/AKT/mTOR pathway (n=… aberrations putatively activating the PI3K/AKT/mTOR pathway, …

… the AKT and ERK survival pathways in hepatocellular carcinoma … AKT and ERK and
proliferation mediated via these pathways, suggesting that JAK/STAT acts upstream of ERK and AKT…