Lymphoid chemokine B cell-attracting chemokine-1 (CXCL13) is expressed in germinal center of ectopic lymphoid follicles within the synovium of chronic arthritis …

K Shi, K Hayashida, M Kaneko… - The Journal of …, 2001 - journals.aai.org
… Many chemokines have been reported and they are classified into two groups as pro-…
chemokines and lymphoid chemokines. BCA-1 has been classified as a lymphoid chemokine so far…

[HTML][HTML] Regulation of the germinal center response

M Stebegg, SD Kumar, A Silva-Cayetano… - Frontiers in …, 2018 - frontiersin.org
… Secondary lymphoid organs are divided into distinct regions through the generation of
chemokine gradients by stromal cells. In the lymph node (LN), these chemokine gradients allow …

RGS13 regulates germinal center B lymphocytes responsiveness to CXC chemokine ligand (CXCL) 12 and CXCL13

GX Shi, K Harrison, GL Wilson, C Moratz… - The Journal of …, 2002 - journals.aai.org
… Located within lymphoid tissues, germinal centers are sites critical for the generation of B …
of germinal centers, activated B cells and select T cells must migrate into the germinal center

The primary germinal center response in mice

CL Cozine, KL Wolniak, TJ Waldschmidt - Current opinion in immunology, 2005 - Elsevier
… that chemokines are central to the development, organization and maintenance of lymphoid
… of homing, and implicates the action of distinct chemokines in compartmentalizing GCs. …

[HTML][HTML] Expression of CXCL13, a chemokine highly upregulated in germinal center T-helper cells, distinguishes angioimmunoblastic T-cell lymphoma from peripheral …

KL Grogg, AD Attygale, WR Macon, ED Remstein… - Modern Pathology, 2006 - Elsevier
… CXCL13 positive cells in normal and reactive lymph nodes were also concentrated in the
germinal centers, including follicular dendritic cells, histiocytes, and rare small lymphocytes (…

Essential role of RelB in germinal center and marginal zone formation and proper expression of homing chemokines

DS Weih, ZB Yilmaz, F Weih - The Journal of Immunology, 2001 - journals.aai.org
… , lymph nodes, and Peyer’s patches. In spleen, RelB is expressed in periarteriolar lymphatic
sheaths, germinal centers … In contrast, expression of homing chemokines is strongly reduced …

CXCL13 is a plasma biomarker of germinal center activity

C Havenar-Daughton, M Lindqvist… - Proceedings of the …, 2016 - National Acad Sciences
chemokine CXCL13 [chemokine (CXC motif) ligand 13] as a biomarker of germinal center
plasma CXCL13 concentrations and germinal center frequencies in lymph nodes in a series of …

[HTML][HTML] T cell subsets in the germinal center: lessons from the macaque model

M Vaccari, G Franchini - Frontiers in immunology, 2018 - frontiersin.org
Germinal centers (GCs) are organized lymphoid tissue microstructures where B cells … CXC
chemokine receptor type 5 (CXCR5) while losing the T cell zone–homing chemokine receptor …

A chemokine-driven positive feedback loop organizes lymphoid follicles

KM Ansel, VN Ngo, PL Hyman, SA Luther, R Förster… - Nature, 2000 - nature.com
… We conclude that the requirement for BLC to induce LTα1β2 is overridden in germinal
centres, most likely by T-cell-derived signals. CD40 signalling is necessary for germinal centre

Unique gene expression program of human germinal center T helper cells

CH Kim, HW Lim, JR Kim, L Rott, P Hillsamer… - Blood, 2004 - ashpublications.org
chemokine CXCL13, a feature consistent with their specific localization in germinal centers.
… can express CXCL13 in germinal centers of secondary lymphoid tissues and chronically …