… Hepatocellular carcinoma (HCC) is a primary liver cancer with high incidence rate, especially
in regions with high prevalence of viral hepatitis infection. Autoimmune disorders, diabetes …

Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide, which ranks
as the sixth of cancer-related death. Despite the emergence of targeted therapy, advanced-…

Primary liver cancer is one of the commonest causes of death. Hepatocellular carcinoma (HCC)
accounts for 90% of primary liver cancers. For patients with unresectable or metastatic …

… Observations This review summarizes rapidly emerging clinical data on the promise and
challenges of implementing ICBs in HCC and discusses the unmet need of biomarkers to …

… In particular, tcDNA methylation analysis shows much promise as an early diagnostic and
… HCC immunotherapy holds great promise but also faces many challenges. Currently, there …

… Immune checkpoint inhibitors (CPIs) offer great promise in the treatment of a rapidly expanding
… How shall we face the opportunities and challenges? Can we dramatically improve the …

… Hepatocellular carcinoma (HCC) is a lethal disease in most patients, due to its aggressive
course and a lack of effective systemic therapies for advanced disease. Surgical resection …

… Hepatocellular carcinoma (HCC) is one of the major causes … made the treatment decision
challenging. The potential curative … Many molecularly targeted therapies has shown promise in …

Hepatocellular carcinoma (HCC) is a major cause of cancer death and is increasing in
incidence. This review focuses on HCC surveillance and treatment of early-stage disease, which …

… While we are beginning to see some promise of improved therapeutic options (summarized
in Table 2 ), a great need for further investigation exists. We strongly encourage all patients …