Optical imaging is a powerful modality in biological discovery. The mainstream of optical
interrogations, however, largely relies on microscopy, which imposes depth limitations on …

Multi-Spectral Optoacoustic Tomography (MSOT) merges the power of high-resolution
imaging at tissue depths of several millimeters to centimeters with the advantages of optical …

Visualization of dynamic functional and molecular events in an unperturbed in vivo
environment is essential for understanding the complex biology of living organisms and of …

For centuries, biological discoveries were based on optical imaging, in particular microscopy
but also several chromophoric assays and photographic approaches. With the recent …

The ability to non-invasively visualize endogenous chromophores and exogenous probes
and sensors across the entire rodent brain with the high spatial and temporal resolution has …

High-resolution volumetric optical imaging modalities, such as confocal microscopy, two-
photon microscopy, and optical coherence tomography, have become increasingly …

Optoacoustic imaging is emerging as a noninvasive imaging modality that can resolve
optical contrast through several millimeters to centimeters of tissue with the resolution …

A major difficulty arising from whole-body optoacoustic imaging is the long acquisition times
associated with recording signals from multiple spatial projections. The acquired signals are …

Optoacoustic imaging, or photoacoustic imaging, is insensitive to photon scattering within
biological tissue and, unlike conventional optical imaging methods, makes high-resolution …

Brain research depends strongly on imaging for assessing function and disease in vivo. We
examine herein multispectral opto-acoustic tomography (MSOT), a novel technology for high …