Subanesthetic ketamine evokes rapid and long-lasting antidepressant effects in human
patients. The mechanism for ketamine's effects remains elusive, but ketamine may broadly …

Ketamine has been described as a fast‐acting antidepressant, exerting effects in depressed
patients and in preclinical models with a rapid onset of action. The typical antidepressant …

Subanesthetic ketamine evokes rapid antidepressant effects in human patients that persist
long past ketamine's chemical half-life of~ 2 h. Ketamine's sustained antidepressant action …

Emerging technologies are now giving us unprecedented access to manipulate brain
circuits, shedding new light on treatments for amblyopia. This research is identifying key …

Background The rapid-acting clinical effects of ketamine as a novel treatment for depression
along with its complex pharmacology have made it a growing research area. One of the key …

Experience‐dependent critical period (CP) plasticity has been extensively studied in the
visual cortex. Monocular deprivation during the CP affects ocular dominance, limits visual …

Amblyopia is the most common form of impairment of visual function affecting one eye, with
a prevalence of about 1–5% of the total world population. This pathology is caused by early …

In this introductory article, we summarize the evidence from humans and animal models on
the shaping of postnatal visual development by focused binocular input. When balanced …

Defined windows in development exist when neural circuitry can be robustly restructured in
response to experience. These time-limited critical periods are shown across many brain …

Amblyopia is a developmental visual disorder resulting from atypical binocular experience in
early childhood that leads to abnormal visual cortex development and vision impairment …