Background Loiasis–a filarial disease endemic in Central and West Africa–is increasingly
recognized as significant individual and public health concern. While the understanding of …

Background Loiasis is mostly considered a relatively benign infection when compared with
other filarial and parasitic diseases, with Calabar swellings and eyeworm being the most …

Background Loiasis is a highly prevalent helminth infection found in distinct regions of sub-
Saharan Africa. The disease has been considered to be of minor clinical significance, but …

Background Chronic infection by Loa loa remains an unsolved immunological paradox.
Despite harboring subcutaneously migrating adult worms and often high densities of …

Abstract Background Loiasis (Loa loa filariasis) is considered a benign disease and is
currently not included in the World Health Organization's (WHO's) list of Neglected Tropical …

Human filariasis due to Loa loa differs from other filariasis in that the majority of infected
subjects are without circulating microfilariae (occult loiasis). In search for alternative …

ABSTRACT Background Detection of Loa loa microfilariae in peripheral blood is insensitive
given only 30% of individuals are microfilaraemic while 70% are amicrofilaraemic with a …

Background The parasitic disease loiasis is associated with significant morbidity and
mortality. Individuals with hyper-microfilaremia (greater than 20,000 microfilariae per mL of …

Background The burden of loiasis has received limited attention and loiasis is still
considered a benign condition. To assess whether loiasis bears any excess mortality, we did …

Loa loa, the African eye worm, is a filarial pathogen transmitted by blood-sucking flies of the
genus Chrysops. Loiasis primarily affects rural populations residing in the forest and …