Abnormal neurotransmission is central to schizophrenia (SZ). Alterations across multiple
neurotransmitter systems in SZ suggest that this illness may be associated with …

The AKT-mTOR signaling transduction pathway plays an important role in
neurodevelopment and synaptic plasticity. mTOR is a serine/threonine kinase that …

The mammalian target of rapamycin (mTOR) signalling cascade is involved in the
intracellular regulation of protein synthesis, specifically for proteins involved in controlling …

Disrupted neuronal protein kinase B (Akt) signaling has been associated with dopamine
(DA)-related neuropsychiatric disorders, including schizophrenia, a devastating mental …

The Akt family of kinases exerts many of its cellular effects via the activation of the
mammalian target of rapamycin (mTOR) kinase through a series of intermediary proteins …

The mammalian target of rapamycin (mTOR) complex 2 (mTORC2) is a multimeric signaling
unit that phosphorylates protein kinase B/Akt following hormonal and growth factor …

Bipolar disorder (BPD) is a severe mental illness characterized by episodes of depression
and mania. To investigate the molecular mechanisms underlying the pathophysiology of …

The mechanistic target of rapamycin (also known as mammalian target of
rapamycin)(mTOR)-dependent signaling pathway plays an important role in protein …

We previously reported a schizophrenia-associated polymorphic CT di-nucleotide repeat
(DNR) at the 5′-untranslated repeat (UTR) of DPYSL2, which responds to mammalian …

The mammalian target of rapamycin (mTOR) is an ubiquitously expressed serine-threonine
kinase, which senses and integrates several intracellular and environmental cues to …