Peptidome: Chaos or inevitability

I Lyapina, V Ivanov, I Fesenko - International journal of molecular …, 2021 - mdpi.com
Thousands of naturally occurring peptides differing in their origin, abundance and possible
functions have been identified in the tissue and biological fluids of vertebrates, insects, fungi …

Exploiting natural peptide diversity: novel research tools and drug leads

K Adermann, H John, L Ständker… - Current opinion in …, 2004 - Elsevier
During the course of evolution, nature has developed a vast number of peptides in all living
and past species that display an exceeding diversity of structure and biological effects, such …

Digging deep into peptidomics applied to body fluids

R Vitorino - Proteomics, 2018 - Wiley Online Library
Peptidomics techniques have allowed the identification of thousands of peptides that are
derived from proteins in body fluids, despite the considerable challenges behind sample …

Mass spectrometry in the discovery of peptides involved in intercellular communication: From targeted to untargeted peptidomics approaches

KT Fan, CW Hsu, YR Chen - Mass Spectrometry Reviews, 2023 - Wiley Online Library
Endogenous peptide hormones represent an essential class of biomolecules, which
regulate cell–cell communications in diverse physiological processes of organisms. Mass …

The peptidomics concept

P Schulz-Knappe, M Schrader… - … chemistry & high …, 2005 - ingentaconnect.com
Peptides are a paramount example of how nature diversifies from one single gene to
release multiple, regulated functionalities at the desired sites and time. To achieve this …

Peptidomics: divide et impera

M Soloviev - Peptidomics: Methods and Protocols, 2010 - Springer
The term “peptidomics” can be defined as the systematic analysis of the peptide content
within a cell, organelle, tissue or organism. The science of peptidomics usually refers to the …

Origins, Technological Advancement, and Applications of Peptidomics

M Schrader - Peptidomics: Methods and Strategies, 2024 - Springer
Peptidomics is the comprehensive characterization of peptides from biological sources
instead of heading for a few single peptides in former peptide research. Mass spectrometry …

Exploring the potential of bioactive peptides: From natural sources to therapeutics

K Purohit, N Reddy, A Sunna - International Journal of Molecular …, 2024 - mdpi.com
Bioactive peptides, specific protein fragments with positive health effects, are gaining
traction in drug development for advantages like enhanced penetration, low toxicity, and …

Investigating endogenous peptides and peptidases using peptidomics

AD Tinoco, A Saghatelian - Biochemistry, 2011 - ACS Publications
Rather than simply being protein degradation products, peptides have proven to be
important bioactive molecules. Bioactive peptides act as hormones, neurotransmitters, and …

Peptidomics: bridging the gap between proteome and metabolome

M Soloviev, P Finch - Proteomics, 2006 - Wiley Online Library
Studies of naturally occurring peptides and protein profiling by 'classical'proteomics are
linked by common analytical objectives and methodologies. The first international workshop …