Elevated cannabinoid 1 receptor mRNA is linked to eating disorder related behavior and attitudes in females with eating disorders

H Frieling, H Albrecht, S Jedtberg, A Gozner… - …, 2009 - Elsevier
OBJECTIVE: The endocannabinoid system is involved in the regulation of appetite, food
intake and energy balance. METHODS: To study possible differences in CB1 and CB2 …

Lower levels of cannabinoid 1 receptor mRNA in female eating disorder patients: association with wrist cutting as impulsive self-injurious behavior

M Schroeder, C Eberlein, M de Zwaan… - …, 2012 - Elsevier
The cannabinoid 1 (CB 1) receptor as the primary mediator of the endocannabinoid (EC)
system was found to play a role in eating disorders (EDs), depression, anxiety, and suicidal …

Brain type 1 cannabinoid receptor availability in patients with anorexia and bulimia nervosa

N Gérard, G Pieters, K Goffin, G Bormans… - Biological …, 2011 - Elsevier
BACKGROUND: The endocannabinoid system is a possible target in the treatment of eating
disorders. We used positron emission tomography to investigate the type 1 cannabinoid …

A nonsynonymous polymorphism in cannabinoid CB2 receptor gene is associated with eating disorders in humans and food intake is modified in mice by its ligands

H Ishiguro, O Carpio, Y Horiuchi, A Shu, S Higuchi… - Synapse, 2010 - Wiley Online Library
Marijuana use activates cannabinoid receptors (CB‐Rs) producing several behavioral
effects related to addiction, mood, and appetite. We investigated the association between …

Altered pattern of cannabinoid type 1 receptor expression in adipose tissue of dysmetabolic and overweight patients

R Sarzani, M Bordicchia, P Marcucci, S Bedetta… - Metabolism, 2009 - Elsevier
In overweight patients (OW), the increased peripheral activity of the endocannabinoid
system in visceral adipose tissue (VAT) may be mediated by cannabinoid type 1 (CB1) …

Overexpression of cannabinoid CB2 receptor in the brain induces hyperglycaemia and a lean phenotype in adult mice

SY Romero‐Zerbo, MS Garcia‐Gutierrez… - Journal of …, 2012 - Wiley Online Library
It is well known that the endocannabinoid system, through cannabinoid CB1 receptor
activation, has an important role in the main aspects of energy balance (ie food intake …

The role of the endocannabinoid system in eating disorders: neurochemical and behavioural preclinical evidence

M Scherma, L Fattore, M Paola Castelli… - Current …, 2014 - ingentaconnect.com
The endocannabinoid system has long been known as a modulator of several physiological
functions, among which the homeostatic and hedonic aspects of eating. CB1 receptors are …

On the role of central type-1 cannabinoid receptor gene regulation in food intake and eating behaviors

M Pucci, E Zaplatic, MV Micioni Di Bonaventura… - International Journal of …, 2021 - mdpi.com
Different neuromodulatory systems are involved in long-term energy balance and body
weight and, among these, evidence shows that the endocannabinoid system, in particular …

Reduced cannabinoid receptor 1 protein in subcutaneous adipose tissue of obese

MF Bennetzen, TS Nielsen, SK Paulsen… - European journal of …, 2010 - Wiley Online Library
Eur J Clin Invest 2010; 40 (2): 121–126 Abstract Background Cannabinoid 1 receptors are
identified in various tissues involved in the internal metabolism including adipose tissue and …

The multiple functions of the endocannabinoid system: a focus on the regulation of food intake

E Tibiriça - Diabetology & metabolic syndrome, 2010 - Springer
Background Cannabis sativa (also known as marijuana) has been cultivated by man for
more than 5,000 years. However, there was a rise in its use in the 20 th century for …