Endothelial invasive response in a co‐culture model with physically‐induced osteodifferentiation
SB Traphagen, I Titushkin, S Sun… - Journal of tissue …, 2013 - Wiley Online Library
Manipulation of stem cells using physicochemical stimuli has emerged as an important tool
in regenerative medicine. While 2D substrates with tunable elasticity have been studied for …
in regenerative medicine. While 2D substrates with tunable elasticity have been studied for …
Endothelial cells support osteogenesis in an in vitro vascularized bone model developed by 3D bioprinting
Bone is a highly vascularized tissue, in which vascularization and mineralization are
concurrent processes during skeletal development. Indeed, both components should be …
concurrent processes during skeletal development. Indeed, both components should be …
Enhanced bone tissue regeneration of a biomimetic cellular scaffold with co‐cultured MSCs‐derived osteogenic and angiogenic cells
L Li, J Li, Q Zou, Y Zuo, B Cai, Y Li - Cell proliferation, 2019 - Wiley Online Library
Objectives The bone tissue engineering primarily focuses on three‐dimensional co‐culture
systems, which physical and biological properties resemble the cell matrix of actual tissues …
systems, which physical and biological properties resemble the cell matrix of actual tissues …
In vitro model of vascularized bone: synergizing vascular development and osteogenesis
Tissue engineering provides unique opportunities for regenerating diseased or damaged
tissues using cells obtained from tissue biopsies. Tissue engineered grafts can also be used …
tissues using cells obtained from tissue biopsies. Tissue engineered grafts can also be used …
Osteogenic stimulatory conditions enhance growth and maturation of endothelial cell microvascular networks in culture with mesenchymal stem cells
TO Pedersen, AL Blois, Y Xue, Z Xing… - Journal of tissue …, 2012 - journals.sagepub.com
To optimize culture conditions for in vitro prevascularization of tissue-engineered bone
constructs, the development of organotypic blood vessels under osteogenic stimulatory …
constructs, the development of organotypic blood vessels under osteogenic stimulatory …
Endothelial microvascular networks affect gene-expression profiles and osteogenic potential of tissue-engineered constructs
Introduction A major determinant of the potential size of cell/scaffold constructs in tissue
engineering is vascularization. The aims of this study were twofold: first to determine the in …
engineering is vascularization. The aims of this study were twofold: first to determine the in …
Modulation of In Vitro Angiogenesis in a Three-Dimensional Spheroidal Coculture Model for Bone Tissue Engineering
A Wenger, A Stahl, H Weber, G Finkenzeller… - Tissue …, 2004 - liebertpub.com
One of the major challenges in tissue engineering of bone substitutes remains
vascularization of the transplant. We have developed a three-dimensional collagen-based …
vascularization of the transplant. We have developed a three-dimensional collagen-based …
Contrasting effects of vasculogenic induction upon biaxial bioreactor stimulation of mesenchymal stem cells and endothelial progenitor cells cocultures in three …
Clinical translation of bone tissue engineering approaches for fracture repair has been
hampered by inadequate vascularization required for maintaining cell survival, skeletal …
hampered by inadequate vascularization required for maintaining cell survival, skeletal …
Endothelial cells enhance the in vivo bone-forming ability of osteogenic cell sheets
Addressing the problem of vascularization is of vital importance when engineering three-
dimensional (3D) tissues. Endothelial cells are increasingly used in tissue-engineered …
dimensional (3D) tissues. Endothelial cells are increasingly used in tissue-engineered …
Cooperation between osteoblastic cells and endothelial cells enhances their phenotypic responses and improves osteoblast function
Osteogenesis requires close co-operation with angiogenesis to create vascularized bone
tissue. In this study, an indirect co-culture model using osteoblasts (OBs), primary …
tissue. In this study, an indirect co-culture model using osteoblasts (OBs), primary …