Ample evidence suggests that hepatic macrophages play key roles in the injury and repair
mechanisms during liver disease progression. There are two major populations of hepatic …

Macrophages are a heterogeneous population of innate immune cells and key cellular
components of the liver. Hepatic macrophages consist of embryologically-derived resident …

Macrophages represent a key cellular component of the liver, and are essential for
maintaining tissue homeostasis and ensuring rapid responses to hepatic injury. Our …

The liver is an essential immunological organ due to its gatekeeper position to bypassing
antigens from the intestinal blood flow and microbial products from the intestinal …

Macrophages, which are key cellular components of the liver, have emerged as essential
players in the maintenance of hepatic homeostasis and in injury and repair processes in …

Hepatic macrophages are a remarkably heterogeneous population consisting of self-
renewing tissue-resident phagocytes, termed Kupffer cells (KCs), and recruited …

Macrophages represent a major cell type of innate immunity and have emerged as a critical
player and therapeutic target in many chronic inflammatory diseases. Hepatic macrophages …

Hepatic macrophages are central in the pathogenesis of chronic liver injury and have been
proposed as potential targets in combatting fibrosis. Recent experimental studies in animal …

Macrophages hold a critical position in the pathogenesis of liver injury and repair, in which
their infiltrations is regarded as a main feature for both acute and chronic liver diseases. It is …

Hepatocytes, the major parenchymal cells in the liver, are responsible for a variety of cellular
functions including carbohydrate, lipid and protein metabolism, detoxification and immune …