Introduction Aim was to develop a full automatic clustering approach of the time-activity
curves (TAC) from dynamic 18F-FET PET and evaluate its association with IDH1 mutation …

Background Glioma grading with dynamic 18 F-FET PET (0–40 min pi) is typically performed
by analysing the mean time-activity curve of the entire tumour or a suspicious area within a …

Purpose For the clinical evaluation of O-(2-18 F-fluoroethyl)-l-tyrosine (18 F-FET) PET
images, the use of standard summation images obtained 20–40 min after injection is …

Background We aimed to elucidate the place of dynamic O-(2-[18F]-fluoroethyl)-L-tyrosine
(18F-FET) PET in prognostic models of gadolinium (Gd)-negative gliomas. Methods In 98 …

In suspected grade II gliomas, three distinct patterns of time–activity curves (TAC) on O‐(2‐
[18F] fluoroethyl)‐1‐tyrosine (18F‐FET) positron emission tomography (PET) have been …

In glioma patients, differentiation between tumor progression (TP) and treatment-related
changes (TRCs) remains challenging. Difficulties in classifying imaging alterations may …

Mutations in isocitrate dehydrogenase (IDH) represent an independent predictor of better
survival in patients with gliomas. We aimed to assess grade and IDH mutation status in …

Purpose The molecular features isocitrate dehydrogenase (IDH) mutation and 1p/19q co-
deletion have gained major importance for both glioma typing and prognosis and have …

Background The present study aimed to explore the efficacy of easily obtained intratumoral
heterogeneous parameters, other than regular semi-quantitative parameters, based on static …

Purpose The purpose of the study is to assess the contribution of 18 F-fluoro-ethyl-tyrosine
(18 F-FET) positron emission tomography (PET) in the delineation of gross tumor volume …